Interactor 1: CLPP (Q16740)
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Caseinolytic mitochondrial matrix peptidase proteolytic subunit) (Endopeptidase Clp)
Gene: CLPP

Interactor 2: PREP (Q5JRX3)
Presequence protease, mitochondrial (hPreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1)
Gene: PITRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 31056398, 32628020
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006508 - proteolysis
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 277
Hs

1 1037
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025