Interactor 1: RIGI (Q6Q899)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI
Interactor 2: MAVS (Q8VCF0)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS
Species: Mus musculus
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.754 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD_2~CARD_2, CARD_2~RIG-I_C |
| Common GO terms | GO:0002230 - positive regulation of defense response to virus by host GO:0002735 - positive regulation of myeloid dendritic cell cytokine production GO:0032727 - positive regulation of interferon-alpha production GO:0032728 - positive regulation of interferon-beta production GO:0032755 - positive regulation of interleukin-6 production and 5 others more... |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
