Protein: Z512B
Zinc finger protein 512B

Gene: Z512B, ZNF512B
Organism: Homo sapiens
Interactions: 200
UniProt ID: Q96KM6

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0008270 - zinc ion binding
GO:1902894 - negative regulation of miRNA transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

913894

ZN143
Zinc finger protein 143

2

18

High-throughput

0.783

High

1116563

FHL3
Four and a half LIM domains protein 3

7

11

High-throughput

0.750

High

1066447

RBBP4
Histone-binding protein RBBP4

6

5

High-throughput

0.735

High

1093923

TRAF1
TNF receptor-associated factor 1

4

8

High-throughput

0.698

High

1102630

MTA1
Metastasis-associated protein MTA1

4

5

High-throughput

0.694

High

1132897

CHD4
Chromodomain-helicase-DNA-binding protein 4

4

15

High-throughput

0.686

High

352223

MBD3
Methyl-CpG-binding domain protein 3

4

4

Small-scale

0.678

High

998690

H31
Histone H3.1

4

20

High-throughput

0.676

High

1109992

HDAC1
Histone deacetylase 1

3

8

High-throughput

0.675

High

1158960

RBBP7
Histone-binding protein RBBP7

3

5

High-throughput

0.667

High

1095099

KLF10
Krueppel-like factor 10

1

20

High-throughput

0.656

High

1088508

CHD3
Chromodomain-helicase-DNA-binding protein 3

3

15

High-throughput

0.656

High

316947

MTA2
Metastasis-associated protein MTA2

3

5

High-throughput

0.650

High

1295287

P66A
Transcriptional repressor p66-alpha

3

2

High-throughput

0.650

High

1360988

P66B
Transcriptional repressor p66-beta

3

2

High-throughput

0.650

High

675630

TYY1
Transcriptional repressor protein YY1

1

19

High-throughput

0.618

High

1396128

BC11A
BCL11 transcription factor A

1

12

High-throughput

0.618

High

1396159

KLF12
Krueppel-like factor 12

1

19

High-throughput

0.618

High

1396116

MTA3
Metastasis-associated protein MTA3

2

8

High-throughput

0.611

High

1396141

MBD2
Methyl-CpG-binding domain protein 2

2

4

High-throughput

0.611

High

1332011

BANP
Protein BANP

2

2

High-throughput

0.606

High

1394153

AJUBA
LIM domain-containing protein ajuba

2

8

High-throughput

0.606

High

1396109

NACC1
Nucleus accumbens-associated protein 1

2

20

High-throughput

0.606

High

558332

XRCC6
X-ray repair cross-complementing protein 6

2

2

High-throughput

0.600

High

168309

HAT1
Histone acetyltransferase type B catalytic subunit

2

0

High-throughput

0.585

High

980153

H4
Histone H4

2

6

High-throughput

0.584

High

981016

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

1307768

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

4

High-throughput

0.573

High

1063532

GOGA2
Golgin subfamily A member 2

2

13

High-throughput

0.553

High

1144863

RABE1
Rab GTPase-binding effector protein 1

2

9

High-throughput

0.553

High

1156183

ZYX
Zyxin

2

8

High-throughput

0.553

High

1205934

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

15

High-throughput

0.553

High

1396113

MDFI
MyoD family inhibitor

2

3

High-throughput

0.553

High

138747

IMA4
Importin subunit alpha-4

1

8

High-throughput

0.536

High

142605

IMA3
Importin subunit alpha-3

1

8

High-throughput

0.536

High

396727

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

814843

CUX1
Homeobox protein cut-like 1

1

19

High-throughput

0.536

High

884384

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.536

High

1396124

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

1

High-throughput

0.536

High

1396133

KAT8
Histone acetyltransferase KAT8

1

2

High-throughput

0.536

High

709152

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.513

High

948575

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1279218

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.513

High

1396140

UBIP1
Upstream-binding protein 1

1

0

High-throughput

0.513

High

130579

SPT5H
Transcription elongation factor SPT5

1

5

High-throughput

0.508

High

177290

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

5

High-throughput

0.508

High

225327

HTSF1
17S U2 SnRNP complex component HTATSF1

1

8

High-throughput

0.508

High

342293

BRD1
Bromodomain-containing protein 1

1

3

High-throughput

0.508

High

855496

ATRX
Transcriptional regulator ATRX

1

20

High-throughput

0.508

High

1153992

SMAD1
Mothers against decapentaplegic homolog 1

1

2

High-throughput

0.508

High

1273154

KDM3B
Lysine-specific demethylase 3B

1

4

High-throughput

0.508

High

1287975

PB1
Protein polybromo-1

1

5

High-throughput

0.508

High

1324584

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

High-throughput

0.508

High

1396118

TRAF4
TNF receptor-associated factor 4

1

17

High-throughput

0.508

High

1396121

PAPP2
Pappalysin-2

1

1

High-throughput

0.508

High

1396135

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

1

High-throughput

0.508

High

1396137

RNC
Ribonuclease 3

1

6

High-throughput

0.508

High

1396144

ZMYM2
Zinc finger MYM-type protein 2

1

1

High-throughput

0.508

High

1396151

KMT2B
Histone-lysine N-methyltransferase 2B

1

8

High-throughput

0.508

High

1396154

KDM2A
Lysine-specific demethylase 2A

1

4

High-throughput

0.508

High

1361823

RSPH1
Radial spoke head 1 homolog

1

2

High-throughput

0.494

High

1396106

SNX27
Sorting nexin-27

1

7

High-throughput

0.489

High

1396158

RPGF2
Rap guanine nucleotide exchange factor 2

1

4

High-throughput

0.489

High

822820

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.486

High

888807

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

0

High-throughput

0.486

High

1032852

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.486

High

1287204

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.486

High

1396111

NIBA2
Protein Niban 2

1

0

High-throughput

0.486

High

1396138

ZHANG
CREB/ATF bZIP transcription factor

1

0

High-throughput

0.486

High

987165

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

High-throughput

0.481

High

1396104

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

14

High-throughput

0.481

High

1396147

MBD1
Methyl-CpG-binding domain protein 1

1

10

High-throughput

0.481

High

66848

DUXA
Double homeobox protein A

1

6

High-throughput

0.479

High

129337

MEN1
Menin

1

2

High-throughput

0.479

High

143194

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

155341

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.479

High

191051

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

8

High-throughput

0.479

High

210089

CRX
Cone-rod homeobox protein

1

15

High-throughput

0.479

High

210332

PHF1
PHD finger protein 1

1

3

High-throughput

0.479

High

243702

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

16

High-throughput

0.479

High

254411

CC14B
Dual specificity protein phosphatase CDC14B

1

2

High-throughput

0.479

High

274367

SIN3B
Paired amphipathic helix protein Sin3b

1

3

High-throughput

0.479

High

285417

EED
Polycomb protein EED

1

8

High-throughput

0.479

High

298432

DNJC8
DnaJ homolog subfamily C member 8

1

8

High-throughput

0.479

High

355582

NSD2
Histone-lysine N-methyltransferase NSD2

1

10

Small-scale

0.479

High

386108

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

13

High-throughput

0.479

High

406514

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

474214

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

487639

PARP1
Poly [ADP-ribose] polymerase 1

1

11

High-throughput

0.479

High

520295

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

634582

LMNB1
Lamin-B1

1

12

High-throughput

0.479

High

643986

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

685312

PAX6
Paired box protein Pax-6

1

5

High-throughput

0.479

High

696235

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

697220

APEX1
DNA repair nuclease/redox regulator APEX1

1

3

High-throughput

0.479

High

703363

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

16

High-throughput

0.479

High

800054

COIL
Coilin

1

2

High-throughput

0.479

High

877547

LHX1
LIM/homeobox protein Lhx1

1

12

High-throughput

0.479

High

883660

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

895778

LHX2
LIM/homeobox protein Lhx2

1

12

High-throughput

0.479

High

905041

MECP2
Methyl-CpG-binding protein 2

1

10

High-throughput

0.479

High

979142

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

984908

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

1017121

H33
Histone H3.3

1

20

High-throughput

0.479

High

1037811

IRF8
Interferon regulatory factor 8

1

5

High-throughput

0.479

High

1086805

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

1087949

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1097493

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1135269

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

16

High-throughput

0.479

High

1137461

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1155668

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.479

High

1195584

ARI4B
AT-rich interactive domain-containing protein 4B

1

10

High-throughput

0.479

High

1255103

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1289542

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1313340

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1314366

SLX4
Structure-specific endonuclease subunit SLX4

1

9

High-throughput

0.479

High

1322626

RPTOR
Regulatory-associated protein of mTOR

1

11

High-throughput

0.479

High

1352692

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1368055

HDAC2
Histone deacetylase 2

1

8

High-throughput

0.479

High

1396110

SIN3A
Paired amphipathic helix protein Sin3a

1

3

High-throughput

0.479

High

1396117

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1396119

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1396123

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

1396127

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

1396132

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

1

High-throughput

0.479

High

1396134

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

1396136

SMYD2
N-lysine methyltransferase SMYD2

1

1

High-throughput

0.479

High

1396139

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1396143

LHX3
LIM/homeobox protein Lhx3

1

13

High-throughput

0.479

High

1396145

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1396148

ELF5
ETS-related transcription factor Elf-5

1

12

High-throughput

0.479

High

1396150

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

15

High-throughput

0.479

High

1396153

ASF1A
Histone chaperone ASF1A

1

3

High-throughput

0.479

High

1396155

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

1396156

MTF2
Metal-response element-binding transcription factor 2

1

3

High-throughput

0.479

High

1396157

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

521863

H14
Histone H1.4

1

14

High-throughput

0.470

High

1232524

Q6FHY5
MEOX2 protein

1

7

High-throughput

0.470

High

141618

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

High-throughput

0.464

High

256497

TOM1
Target of Myb1 membrane trafficking protein

1

4

High-throughput

0.464

High

294189

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.464

High

294745

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.464

High

300209

GLRX3
Glutaredoxin-3

1

7

High-throughput

0.464

High

318527

TOX4
TOX high mobility group box family member 4

1

9

High-throughput

0.464

High

463196

YES
Tyrosine-protein kinase Yes

1

5

High-throughput

0.464

High

599305

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

2

High-throughput

0.464

High

642579

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.464

High

773250

MYH10
Myosin-10

1

7

High-throughput

0.464

High

937431

LAMB2
Laminin subunit beta-2

1

3

High-throughput

0.464

High

941522

CTBP2
C-terminal-binding protein 2

1

4

High-throughput

0.464

High

1028846

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

10

High-throughput

0.464

High

1055345

APLP2
Amyloid beta precursor like protein 2

1

10

High-throughput

0.464

High

1123765

DCTN1
Dynactin subunit 1

1

10

High-throughput

0.464

High

1217993

MYOME
Myomegalin

1

12

High-throughput

0.464

High

1371404

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

9

High-throughput

0.464

High

1396108

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.464

High

1396114

LZTS2
Leucine zipper putative tumor suppressor 2

1

16

High-throughput

0.464

High

1396115

CAB45
45 kDa calcium-binding protein

1

8

High-throughput

0.464

High

1396120

BTBD2
BTB/POZ domain-containing protein 2

1

3

High-throughput

0.464

High

1396129

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

5

High-throughput

0.464

High

1396152

INVS
Inversin

1

5

High-throughput

0.464

High

282291

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

519548

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

915476

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.458

High

1198000

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

1216619

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1312682

BAP18
BPTF-associated chromatin complex component 1

1

0

High-throughput

0.458

High

1335450

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.458

High

1357139

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1392557

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

1396122

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

1396149

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1367036

ESR2
Estrogen receptor beta

1

20

High-throughput

0.445

High

225847

AP1G1
AP-1 complex subunit gamma-1

1

2

High-throughput

0.439

High

894097

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.439

High

1024141

TFAM
Transcription factor A, mitochondrial

1

12

High-throughput

0.437

High

1094718

CAF1A
Chromatin assembly factor 1 subunit A

1

5

High-throughput

0.437

High

1133608

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.437

High

1208630

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.437

High

1308365

CCD71
Coiled-coil domain-containing protein 71

1

1

Small-scale

0.437

High

1396105

RHOV
Rho-related GTP-binding protein RhoV

1

16

High-throughput

0.437

High

1396107

PWP2A
PWWP domain-containing protein 2A

1

4

High-throughput

0.437

High

1396112

FEV
Protein FEV

1

10

High-throughput

0.437

High

1396125

SP130
Histone deacetylase complex subunit SAP130

1

5

High-throughput

0.437

High

1396131

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.437

High

1396146

HMGX4
HMG domain-containing protein 4

1

10

High-throughput

0.437

High

684022

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

5

High-throughput

0.417

High

1209086

Q5RKT7
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

High-throughput

0.417

High

1314572

Q8IY97
AP-1 complex subunit gamma

1

2

High-throughput

0.417

High

1396130

CK068
UPF0696 protein C11orf68

2

0

High-throughput

0.316

High

317082

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.279

Low

705514

GRN
Progranulin

1

0

High-throughput

0.279

Low

1093769

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1396126

HDHD2
Haloacid dehalogenase-like hydrolase domain-containing protein 2

1

0

High-throughput

0.279

Low

407772

VWF
von Willebrand factor

1

0

High-throughput

0.265

Low

522724

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.265

Low

1105543

OS9
Protein OS-9

1

0

High-throughput

0.265

Low

1214175

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.265

Low

1293983

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.265

Low

1396142

I36RA
Interleukin-36 receptor antagonist protein

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025