HitPredict

Interactor 1: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35973513, 37120454
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043539 - protein serine/threonine kinase activator activity GO:0060090 - molecular adaptor activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1708 Hs			1 2671
+	Hs
		268762 RICTR_HUMAN (1-1708): 0: 2775: 100.00		SF3B1_HUMAN (1238-2069): 1.02e-61: 236: 13.97
+	Hs
		787507 RICTR_HUMAN (1-1708): 0: 2775: 100.00		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Mm
		1163330 RICTR_MOUSE (1-1708): 0: 2728: 95.38		MTOR_MOUSE (824-2632): 2.47e-34: 147: 12.66
+	Hs
		1047754 RICTR_HUMAN (1-1708): 0: 2775: 100.00		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Hs
		787525 Q8N6M7_HUMAN (1-252): 4.09e-116: 369: 99.60		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46