HitPredict

Interactor 1: I27RA (Q6UWB1)
Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)
Gene: IL27RA

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 280
+	Hs
		1165174 I27RA_HUMAN (1-636): 7.04e-114: 356: 100.00		TMX4_HUMAN (20-261): 3.55e-53: 178: 41.98
+	Hs
		1191160 SDK1_HUMAN (3-629): 2.84e-39: 157: 10.09		TMX1_HUMAN (1-280): 1.13e-79: 243: 100.00
+	Hs
		1310926 FND3A_HUMAN (232-635): 1.81e-31: 133: 10.72		ERP44_HUMAN (1-161): 1.35e-38: 141: 23.12
+	Hs
		363283 FINC_HUMAN (24-396): 8.68e-20: 96.5: 11.54		ERP44_HUMAN (1-161): 1.35e-38: 141: 23.12
+	Hs
		363159 FINC_HUMAN (24-396): 8.68e-20: 96.5: 11.54		PDIA6_HUMAN (25-146): 1.28e-34: 131: 31.01
+	Hs
		423399 FND3A_HUMAN (232-635): 1.81e-31: 133: 10.72		PDIA1_HUMAN (66-256): 1.82e-10: 62.8: 10.68
+	Hs
		531962 COCA1_HUMAN (120-506): 1.17e-13: 76.8: 18.30		PDIA4_HUMAN (119-266): 7.26e-15: 76.3: 9.68
+	Hs
		671883 TITIN_HUMAN (7-429): 2.95e-09: 62.6: 9.73		PDIA3_HUMAN (147-256): 2.92e-14: 74.4: 12.61