HitPredict

Interactor 1: ABRX1 (Q6UWZ7)
BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A)
Gene: ABRAXAS1

Interactor 2: BABA2 (Q9NXR7)
BRISC and BRCA1-A complex member 2 (BRCA1-A complex subunit BRE) (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein)
Gene: BABAM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

The method score is based on:

Property	Details
Experiments	24075985, 19261749, 19261746, 21282113, 19261748, 19615732, 20656689
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006282 - regulation of DNA repair GO:0006302 - double-strand break repair GO:0006325 - chromatin organization and 6 others more... GO:0007095 - mitotic G2 DNA damage checkpoint signaling GO:0010212 - response to ionizing radiation GO:0031593 - polyubiquitin modification-dependent protein binding GO:0044818 - mitotic G2/M transition checkpoint GO:0045739 - positive regulation of DNA repair GO:0070531 - BRCA1-A complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	409
Hs

1	383

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024