Interactor 1: ALKL1 (Q6UXT8)
ALK and LTK ligand 1 (Augmentor beta) (AUG-beta)
Gene: ALKAL1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.589

The method score is based on:

Property Details
Experiments 26418745
Identification Methods surface plasmon resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0030298 - receptor signaling protein tyrosine kinase activator activity
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 129
Hs

1 1620
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024