HitPredict

Interactor 1: DLK2 (Q6UY11)
Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9)
Gene: DLK2

Interactor 2: LRP10 (Q7Z4F1)
Low-density lipoprotein receptor-related protein 10 (LRP-10)
Gene: LRP10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 383 Hs			1 713
+	Hs
		351079 DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00		LDLR_HUMAN (52-329): 1.21e-22: 105: 10.65
+	Hs
		980582 NOTC2_HUMAN (98-263): 4.59e-26: 112: 28.99		ST14_HUMAN (6-300): 5.21e-37: 150: 14.65
+	Hs
		957618 DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00		LRP2_HUMAN (344-521): 1.01e-09: 64.6: 20.33
+	Hs
		1376965 JAG2_HUMAN (47-383): 1e-22: 102: 21.04		ST14_HUMAN (6-300): 5.21e-37: 150: 14.65
+	Hs
		1357254 NOTC3_HUMAN (46-255): 3.83e-14: 76.3: 31.65		ST14_HUMAN (6-300): 5.21e-37: 150: 14.65
+	Hs
		296681 SLIT2_HUMAN (175-286): 8.64e-10: 62.8: 19.67		ST14_HUMAN (6-300): 5.21e-37: 150: 14.65
+	Dm
		246971 TENM_DROME (211-368): 1.91e-25: 110: 12.42		Q9VBN0_DROME (263-523): 7.01e-19: 93.9: 19.32
+	Dm
		422964 NOTCH_DROME (8-254): 4.99e-15: 78.9: 19.93		Q9W4Y4_DROME (86-476): 3.78e-25: 114: 12.74
+	Hs
		992726 NOTC3_HUMAN (46-255): 3.83e-14: 76.3: 31.65		LRP1_HUMAN (176-434): 6.1e-11: 68.4: 10.23