HitPredict

Interactor 1: RBP10 (Q6VN20)
Ran-binding protein 10 (RanBP10)
Gene: RANBP10

Interactor 2: GID8 (Q9NWU2)
Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1)
Gene: GID8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	27173435, 33961781, 35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CTLH~CTLH, CTLH~LisH, LisH~LisH
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 228
+	Hs
		1167148 RBP10_HUMAN (1-620): 0: 751: 100.00		MAEA_HUMAN (24-227): 1.88e-50: 170: 21.80
+	Hs
		1167182 RBP10_HUMAN (1-620): 0: 751: 100.00		RMD5A_HUMAN (25-206): 3.39e-48: 164: 17.65
+	Hs
		1167162 RBP10_HUMAN (1-620): 0: 751: 100.00		RMD5B_HUMAN (20-194): 2.25e-47: 162: 18.89
+	Hs
		1301810 RANB9_HUMAN (19-620): 0: 665: 66.77		GID8_HUMAN (1-228): 4.34e-78: 236: 100.00
+	Hs
		1185138 RANB9_HUMAN (19-620): 0: 665: 66.77		MAEA_HUMAN (24-227): 1.88e-50: 170: 21.80
+	Hs
		1167168 RBP10_HUMAN (1-620): 0: 751: 100.00		RANB9_HUMAN (115-202): 3.56e-17: 81.7: 25.53
+	Hs
		1301794 RANB9_HUMAN (19-620): 0: 665: 66.77		RMD5A_HUMAN (25-206): 3.39e-48: 164: 17.65
+	Hs
		1291934 RANB9_HUMAN (19-620): 0: 665: 66.77		RMD5B_HUMAN (20-194): 2.25e-47: 162: 18.89
+	Dm
		1119173 RBP9X_DROME (21-617): 0: 567: 47.26		Q9VWS1_DROME (1-225): 1.6e-62: 196: 57.97
+	Hs
		1301759 RANB9_HUMAN (19-620): 0: 665: 66.77		RANB9_HUMAN (115-202): 3.56e-17: 81.7: 25.53
+	At
		1196564 Q94BS7_ARATH (40-442): 3.8e-103: 321: 22.01		GID8_ARATH (3-227): 4.77e-77: 233: 50.67
+	At
		95045 Q94BS7_ARATH (40-442): 3.8e-103: 321: 22.01		F4HTG9_ARATH (42-227): 6.56e-58: 183: 46.24
+	Sc
		858895 VID30_YEAST (116-602): 2.54e-96: 317: 19.88		VID30_YEAST (19-196): 6.67e-29: 115: 20.00
+	Sc
		770363 VID30_YEAST (116-602): 2.54e-96: 317: 19.88		GID8_YEAST (11-197): 1.03e-25: 105: 20.97
+	Sc
		774570 VID30_YEAST (116-602): 2.54e-96: 317: 19.88		FYV10_YEAST (12-152): 1.11e-23: 100: 18.42
+	Dm
		1229016 Q9VWS1_DROME (233-441): 7.78e-49: 171: 15.91		Q8MSB1_DROME (5-213): 1.95e-52: 175: 19.05
+	Dm
		1375220 Q9VWS1_DROME (233-441): 7.78e-49: 171: 15.91		Q9W2N5_DROME (29-206): 2.77e-39: 142: 13.83