HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: PP12C (Q9BZL4)
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)
Gene: PPP1R12C

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.566

Property	Details
Experiments	15469989, 16243315
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1025 Hs			1 782
+	Hs
		1167443 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		ANR50_HUMAN (65-441): 3.02e-68: 248: 19.15
+	Hs
		965125 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		161391 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Hs
		1021434 DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61		ANK3_HUMAN (56-476): 1.58e-62: 231: 16.89
+	Hs
		1153256 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		POTEE_HUMAN (2-655): 3.94e-72: 257: 14.91
+	Hs
		161453 TARA_HUMAN (231-985): 1.44e-51: 201: 35.57		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Hs
		1021404 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		ANK3_HUMAN (56-476): 1.58e-62: 231: 16.89
+	Hs
		161388 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Hs
		965158 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		148138 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Mm
		936588 ROCK2_MOUSE (502-969): 1.57e-40: 165: 18.71		ANS1B_MOUSE (11-156): 1.04e-14: 80.5: 18.79
+	Hs
		1357766 CE164_HUMAN (163-980): 5.02e-36: 150: 11.93		INVS_HUMAN (184-380): 8.23e-18: 90.5: 14.21
+	Hs
		225128 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYPT2_HUMAN (353-782): 4.07e-27: 120: 21.69
+	Hs
		724782 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		725139 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		ANK2_HUMAN (192-510): 1.07e-25: 116: 13.86
+	Hs
		161319 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		MYPT1_HUMAN (542-782): 1.47e-22: 105: 33.61
+	Mm
		57429 MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68		A2AM57_MOUSE (180-380): 2.48e-17: 89: 13.93
+	Rn
		251022 PLEC_RAT (552-958): 2.26e-13: 77.4: 13.74		ANK3_RAT (234-418): 7.27e-22: 104: 12.97
+	Mm
		57440 PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60		A2AM57_MOUSE (180-380): 2.48e-17: 89: 13.93
+	Mm
		57416 Q6S385_MOUSE (494-979): 3.17e-11: 70.1: 14.60		A2AM57_MOUSE (180-380): 2.48e-17: 89: 13.93