HitPredict

Interactor 1: BCOR (Q6W2J9)
BCL-6 corepressor (BCoR)
Gene: BCOR

Interactor 2: YAF2 (Q8IY57)
YY1-associated factor 2
Gene: YAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26496610, 26687479, 27505670, 28514442, 27705803, 24981860, 33961781, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1755 Hs			1 180
+	Hs
		1167270 BCOR_HUMAN (1-1755): 0: 2385: 100.00		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78
+	Hs
		1125887 BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63		YAF2_HUMAN (1-180): 8.51e-73: 218: 100.00
+	Hs
		1125888 BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78
+	Hs
		1233096 ANR44_HUMAN (1120-1620): 8.02e-72: 264: 13.93		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78
+	Hs
		965132 ANK2_HUMAN (1083-1615): 1.81e-68: 259: 14.05		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78
+	Hs
		166966 ANR28_HUMAN (1143-1621): 1.9e-67: 251: 11.51		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78
+	Dm
		1214939 Q8IQT4_DROME (1426-1621): 1.22e-54: 213: 42.50		Q9W215_DROME (1-133): 1.35e-51: 163: 51.13
+	Hs
		1205982 MIB1_HUMAN (1313-1647): 8.4e-44: 176: 14.75		RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78