HitPredict

Interactor 1: BCOR (Q6W2J9)
BCL-6 corepressor (BCoR)
Gene: BCOR

Interactor 2: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	26687479, 27505670, 16943429, 26186194, 28514442, 27705803, 24981860, 33961781, 22325352, 34316702
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1755 Hs			1 228
+	Hs
		1167267 BCOR_HUMAN (1-1755): 0: 2385: 100.00		YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89
+	Hs
		1125888 BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		1125887 BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63		YAF2_HUMAN (3-227): 3.24e-55: 176: 52.89
+	Hs
		1233096 ANR44_HUMAN (1120-1620): 8.02e-72: 264: 13.93		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		965132 ANK2_HUMAN (1083-1615): 1.81e-68: 259: 14.05		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		166966 ANR28_HUMAN (1143-1621): 1.9e-67: 251: 11.51		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Hs
		1205982 MIB1_HUMAN (1313-1647): 8.4e-44: 176: 14.75		RYBP_HUMAN (1-228): 2.79e-61: 193: 100.00
+	Dm
		1214939 Q8IQT4_DROME (1426-1621): 1.22e-54: 213: 42.50		Q9W215_DROME (3-197): 3.06e-42: 142: 37.95