Interactor 1: CERS6 (Q6ZMG9)
Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)
Gene: CERS6

Interactor 2: CERS4 (Q9HA82)
Ceramide synthase 4 (CerS4) (EC 2.3.1.-) (LAG1 longevity assurance homolog 4) (Sphingosine N-acyltransferase CERS4) (EC 2.3.1.24)
Gene: CERS4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain
Common GO terms GO:0003677 - DNA binding
GO:0005789 - endoplasmic reticulum membrane
GO:0030148 - sphingolipid biosynthetic process
GO:0046513 - ceramide biosynthetic process
GO:0050291 - sphingosine N-acyltransferase activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 384
Hs

1 394
+ Hs
+ Hs
+ Zm
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024