HitPredict

Interactor 1: CERS6 (Q6ZMG9)
Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)
Gene: CERS6

Interactor 2: GPR84 (Q9NQS5)
G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33)
Gene: GPR84

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.604

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 384 Hs			1 396
+	Hs
		436927 CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00		ACM4_HUMAN (9-392): 1.08e-72: 236: 16.48
+	Hs
		537300 CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64		DRD2_HUMAN (4-387): 7.78e-75: 241: 20.93
+	Hs
		658250 CERS6_HUMAN (1-384): 8.88e-163: 463: 100.00		5HT2C_HUMAN (40-395): 4.28e-57: 195: 16.85
+	Hs
		656968 CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64		5HT1B_HUMAN (14-391): 8.83e-68: 221: 18.23
+	Hs
		658260 CERS5_HUMAN (6-375): 6.65e-154: 440: 64.96		5HT2C_HUMAN (40-395): 4.28e-57: 195: 16.85
+	Hs
		658276 CERS2_HUMAN (7-342): 1.13e-146: 422: 44.64		5HT2C_HUMAN (40-395): 4.28e-57: 195: 16.85
+	Hs
		537283 TRAM1_HUMAN (120-371): 3.28e-69: 224: 19.46		DRD2_HUMAN (4-387): 7.78e-75: 241: 20.93
+	Hs
		537256 CERS1_HUMAN (113-367): 1.15e-60: 200: 33.09		DRD2_HUMAN (4-387): 7.78e-75: 241: 20.93
+	Hs
		783797 TR1L1_HUMAN (120-342): 4.76e-53: 181: 17.11		5HT2B_HUMAN (21-394): 1.97e-60: 204: 18.70