HitPredict

Interactor 1: SGK1 (O00141)
Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)
Gene: SGK1

Interactor 2: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 12729930, 19953087, 11696533, 20730100
Identification Methods pull down, enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006974 - DNA damage response
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 431
Hs

1 1319
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024