HitPredict

Interactor 1: ARHGI (Q6ZSZ5)
Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)
Gene: ARHGEF18

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RhoGEF~fn3
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1361 Hs			1 783
+	Hs
		1016921 AKP13_HUMAN (16-1282): 1.69e-108: 382: 30.91		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171093 ARHG2_HUMAN (258-1241): 9.19e-103: 353: 29.62		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171081 ARHG1_HUMAN (249-812): 7.94e-95: 328: 25.21		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		551749 DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078848 ITSN1_HUMAN (355-820): 3.79e-79: 290: 18.76		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1049713 ARHG7_HUMAN (253-996): 6.63e-78: 277: 13.14		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170938 PREX1_HUMAN (401-889): 2.18e-73: 272: 14.48		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1066031 ARHG6_HUMAN (306-1038): 6.93e-76: 270: 13.12		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		167093 ARHGB_HUMAN (251-1002): 1.18e-72: 269: 17.57		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171746 ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172040 ARHGC_HUMAN (244-955): 4.05e-71: 264: 18.23		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1273282 ARHG2_HUMAN (258-1241): 9.19e-103: 353: 29.62		TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16
+	Hs
		1078906 ITSN1_HUMAN (355-820): 3.79e-79: 290: 18.76		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		1123297 PKHG4_HUMAN (27-835): 3.45e-71: 263: 12.84		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		1066047 ARHG6_HUMAN (306-1038): 6.93e-76: 270: 13.12		TRI54_HUMAN (198-528): 4.04e-73: 244: 20.71
+	Hs
		1318697 ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31		TRIM7_HUMAN (203-762): 1.89e-73: 249: 15.50
+	Hs
		1232422 ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31		CMYA5_HUMAN (262-606): 5.31e-36: 149: 19.32
+	Hs
		537087 ARHG3_HUMAN (325-825): 8.86e-78: 269: 17.31		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537073 ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		1318728 ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31		TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70