Protein: SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)

Gene: SGTB
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q96EQ0

Gene Ontology (top 5):
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0030544 - Hsp70 protein binding
GO:0042802 - identical protein binding
GO:0051260 - protein homooligomerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543260

UBL4A
Ubiquitin-like protein 4A

3

19

High-throughput

0.858

High

226852

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

3

19

High-throughput

0.836

High

876719

HSP13
Heat shock 70 kDa protein 13

3

20

High-throughput

0.770

High

1086078

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

1

High-throughput

0.700

High

1389495

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

2

1

High-throughput

0.700

High

856859

BAG6
Large proline-rich protein BAG6

1

14

High-throughput

0.691

High

1389532

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.691

High

820538

IL6RB
Interleukin-6 receptor subunit beta

4

5

High-throughput

0.683

High

351582

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

5

10

High-throughput

0.663

High

656220

PPIB
Peptidyl-prolyl cis-trans isomerase B

3

7

High-throughput

0.661

High

573618

ENPL
Endoplasmin

1

20

High-throughput

0.621

High

1389486

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

19

High-throughput

0.621

High

600897

HSP76
Heat shock 70 kDa protein 6

1

20

High-throughput

0.618

High

350619

TXD12
Thioredoxin domain-containing protein 12

3

7

High-throughput

0.616

High

424605

PAI1
Plasminogen activator inhibitor 1

3

5

High-throughput

0.616

High

130204

PGRC1
Membrane-associated progesterone receptor component 1

2

1

High-throughput

0.606

High

220402

LAT
Linker for activation of T-cells family member 1

2

1

High-throughput

0.606

High

270472

FZD7
Frizzled-7

2

1

High-throughput

0.606

High

388273

GLPA
Glycophorin-A

2

3

High-throughput

0.606

High

407508

K2C1
Keratin, type II cytoskeletal 1

2

4

High-throughput

0.606

High

469763

SODE
Extracellular superoxide dismutase [Cu-Zn]

2

3

High-throughput

0.606

High

697985

CALR
Calreticulin

2

10

High-throughput

0.606

High

716216

ERP29
Endoplasmic reticulum resident protein 29

2

18

High-throughput

0.606

High

760768

CD68
Macrosialin

2

1

High-throughput

0.606

High

888500

COMP
Cartilage oligomeric matrix protein

2

9

High-throughput

0.606

High

1228204

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

2

7

High-throughput

0.606

High

1232911

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

2

3

High-throughput

0.606

High

1309795

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

2

4

High-throughput

0.606

High

1389508

EKI1
Ethanolamine kinase 1

2

1

High-throughput

0.606

High

1389509

SDF2L
Stromal cell-derived factor 2-like protein 1

2

3

High-throughput

0.606

High

1389511

TNR19
Tumor necrosis factor receptor superfamily member 19

2

3

High-throughput

0.606

High

1389518

NB5R1
NADH-cytochrome b5 reductase 1

2

4

High-throughput

0.606

High

295430

SPI2
Serpin I2

3

5

High-throughput

0.604

High

1272417

GET4
Golgi to ER traffic protein 4 homolog

2

2

High-throughput

0.601

High

1389487

Q96GW1
HSP90B1 protein

1

20

High-throughput

0.594

High

296629

TNF13
Tumor necrosis factor ligand superfamily member 13

2

0

High-throughput

0.580

High

889941

VEGFC
Vascular endothelial growth factor C

2

0

High-throughput

0.580

High

1322747

PORIM
Porimin

2

0

High-throughput

0.580

High

141945

PODXL
Podocalyxin

2

7

High-throughput

0.553

High

258207

ZG16
Zymogen granule membrane protein 16

2

4

High-throughput

0.553

High

289231

UPK3A
Uroplakin-3a

2

1

High-throughput

0.553

High

353490

AGR2
Anterior gradient protein 2 homolog

2

7

High-throughput

0.553

High

388658

C1QA
Complement C1q subcomponent subunit A

2

13

High-throughput

0.553

High

399414

SLPI
Antileukoproteinase

2

2

High-throughput

0.553

High

404610

TFF1
Trefoil factor 1

2

1

High-throughput

0.553

High

477109

IL6RA
Interleukin-6 receptor subunit alpha

2

9

High-throughput

0.553

High

485949

GIP
Gastric inhibitory polypeptide

2

1

High-throughput

0.553

High

516048

CSH2
Chorionic somatomammotropin hormone 2

2

1

High-throughput

0.553

High

518657

SRGN
Serglycin

2

1

High-throughput

0.553

High

522286

OSTP
Osteopontin

2

1

High-throughput

0.553

High

598269

CL3L1
C-C motif chemokine 3-like 1

2

1

High-throughput

0.553

High

681895

RBTN2
Rhombotin-2

2

2

High-throughput

0.553

High

717226

KCY
UMP-CMP kinase

2

1

High-throughput

0.553

High

726689

SDC4
Syndecan-4

2

1

High-throughput

0.553

High

762413

BTC
Probetacellulin [Cleaved into: Betacellulin

2

4

High-throughput

0.553

High

772293

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

2

5

High-throughput

0.553

High

787831

PEDF
Pigment epithelium-derived factor

2

6

High-throughput

0.553

High

821754

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

2

High-throughput

0.553

High

852677

PPIC
Peptidyl-prolyl cis-trans isomerase C

2

8

High-throughput

0.553

High

898253

R144A
E3 ubiquitin-protein ligase RNF144A

2

8

High-throughput

0.553

High

937607

CAD15
Cadherin-15

2

7

High-throughput

0.553

High

1006282

CTG1B
Cancer/testis antigen 1

2

1

High-throughput

0.553

High

1009697

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.553

High

1030836

DEF6
Defensin-6

2

3

High-throughput

0.553

High

1043644

COAA1

2

5

High-throughput

0.553

High

1098738

NDK3
Nucleoside diphosphate kinase 3

2

3

High-throughput

0.553

High

1142361

PDIA6
Protein disulfide-isomerase A6

2

19

High-throughput

0.553

High

1145653

RCN1
Reticulocalbin-1

2

10

High-throughput

0.553

High

1155025

ADIPO
Adiponectin

2

15

High-throughput

0.553

High

1159220

SGCA
Alpha-sarcoglycan

2

1

High-throughput

0.553

High

1180119

VWC2
Brorin

2

2

High-throughput

0.553

High

1204491

RNS10
Inactive ribonuclease-like protein 10

2

1

High-throughput

0.553

High

1231963

DMKN
Dermokine

2

2

High-throughput

0.553

High

1248853

CE046
Uncharacterized protein C5orf46

2

1

High-throughput

0.553

High

1295793

C1QL4
Complement C1q-like protein 4

2

14

High-throughput

0.553

High

1309551

NNRD
ATP-dependent

2

1

High-throughput

0.553

High

1322579

SHSA5
Protein shisa-5

2

1

High-throughput

0.553

High

1336126

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

2

3

High-throughput

0.553

High

1350291

C99L2
CD99 antigen-like protein 2

2

1

High-throughput

0.553

High

1350306

AGR3
Anterior gradient protein 3

2

7

High-throughput

0.553

High

1360000

WFD12
WAP four-disulfide core domain protein 12

2

1

High-throughput

0.553

High

1369040

GGH
Gamma-glutamyl hydrolase

2

2

High-throughput

0.553

High

1380326

MYDGF
Myeloid-derived growth factor

2

1

High-throughput

0.553

High

1387142

PAUF
Pancreatic adenocarcinoma up-regulated factor

2

4

High-throughput

0.553

High

1389488

RN170
E3 ubiquitin-protein ligase RNF170

2

2

High-throughput

0.553

High

1389490

PRAP1
Proline-rich acidic protein 1

2

1

High-throughput

0.553

High

1389491

GPX7
Glutathione peroxidase 7

2

3

High-throughput

0.553

High

1389493

OSMR
Oncostatin-M-specific receptor subunit beta

2

7

High-throughput

0.553

High

1389494

SYT11
Synaptotagmin-11

2

3

High-throughput

0.553

High

1389496

C1QT6
Complement C1q tumor necrosis factor-related protein 6

2

15

High-throughput

0.553

High

1389497

C1QT5
Complement C1q tumor necrosis factor-related protein 5

2

16

High-throughput

0.553

High

1389499

ABCG4
ATP-binding cassette sub-family G member 4

2

1

High-throughput

0.553

High

1389500

SIL1
Nucleotide exchange factor SIL1

2

1

High-throughput

0.553

High

1389502

SYT4
Synaptotagmin-4

2

3

High-throughput

0.553

High

1389504

EVA1A
Protein eva-1 homolog A

2

1

High-throughput

0.553

High

1389512

FGF21
Fibroblast growth factor 21

2

2

High-throughput

0.553

High

1389520

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

1

High-throughput

0.553

High

1389521

KCNE5
Potassium voltage-gated channel subfamily E regulatory beta subunit 5

2

1

High-throughput

0.553

High

1389526

COLQ
Acetylcholinesterase collagenic tail peptide

2

3

High-throughput

0.553

High

299329

FLOT1
Flotillin-1

1

3

High-throughput

0.536

High

449575

HEXA
Beta-hexosaminidase subunit alpha

1

1

High-throughput

0.536

High

488837

FURIN
Furin

1

5

High-throughput

0.536

High

839339

MTOR
Serine/threonine-protein kinase mTOR

1

8

High-throughput

0.536

High

992909

RACK1
Small ribosomal subunit protein RACK1

1

12

High-throughput

0.536

High

1047075

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

8

High-throughput

0.536

High

1124884

FLOT2
Flotillin-2

1

3

High-throughput

0.536

High

1219322

ECM29
Proteasome adapter and scaffold protein ECM29

1

15

High-throughput

0.536

High

1244895

NCEH1
Neutral cholesterol ester hydrolase 1

1

2

High-throughput

0.536

High

1316761

WDFY3
WD repeat and FYVE domain-containing protein 3

1

10

High-throughput

0.536

High

1351938

RBCC1
RB1-inducible coiled-coil protein 1

1

10

High-throughput

0.536

High

1358950

DNJA4
DnaJ homolog subfamily A member 4

1

17

High-throughput

0.536

High

1389492

DNJC2
DnaJ homolog subfamily C member 2

1

20

High-throughput

0.536

High

1124219

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.513

High

1389510

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.513

High

465976

CO1A2
Collagen alpha-2(I) chain

1

4

High-throughput

0.494

High

1389525

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.494

High

67697

RHG32
Rho GTPase-activating protein 32

1

3

High-throughput

0.489

High

174795

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

5

High-throughput

0.489

High

208136

PLXB1
Plexin-B1

1

3

High-throughput

0.489

High

210468

MSH5
MutS protein homolog 5

1

4

High-throughput

0.489

High

227027

MCAT
Mitochondrial carnitine/acylcarnitine carrier protein

1

8

High-throughput

0.489

High

284206

SRS10
Serine/arginine-rich splicing factor 10

1

4

High-throughput

0.489

High

317207

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

5

High-throughput

0.489

High

464027

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

19

High-throughput

0.489

High

482627

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

4

High-throughput

0.489

High

568165

PLSL
Plastin-2

1

11

High-throughput

0.489

High

592685

ITB4
Integrin beta-4

1

4

High-throughput

0.489

High

896430

ERF
ETS domain-containing transcription factor ERF

1

3

High-throughput

0.489

High

907930

PLXA3
Plexin-A3

1

3

High-throughput

0.489

High

976762

ERF1
Eukaryotic peptide chain release factor subunit 1

1

2

High-throughput

0.489

High

977792

ACTA
Actin, aortic smooth muscle

1

9

High-throughput

0.489

High

1039979

AKA12
A-kinase anchor protein 12

1

10

High-throughput

0.489

High

1102624

MTA1
Metastasis-associated protein MTA1

1

4

High-throughput

0.489

High

1103645

PHLP
Phosducin-like protein

1

2

High-throughput

0.489

High

1118239

BLMH
Bleomycin hydrolase

1

1

High-throughput

0.489

High

1144860

RABE1
Rab GTPase-binding effector protein 1

1

9

High-throughput

0.489

High

1218210

ZN318
Zinc finger protein 318

1

1

High-throughput

0.489

High

1231278

BLT3A
Bridge-like lipid transfer protein family member 3A

1

2

High-throughput

0.489

High

1235930

PDE12
2',5'-phosphodiesterase 12

1

1

High-throughput

0.489

High

1247750

NHS
Actin remodeling regulator NHS

1

8

High-throughput

0.489

High

1295440

C2CD5
C2 domain-containing protein 5

1

5

High-throughput

0.489

High

1317119

ABCA7
Phospholipid-transporting ATPase ABCA7

1

1

High-throughput

0.489

High

1351437

BRX1
Ribosome biogenesis protein BRX1 homolog

1

2

High-throughput

0.489

High

1366819

RAD54
DNA repair and recombination protein RAD54-like

1

8

High-throughput

0.489

High

1389489

ZN668
Zinc finger protein 668

1

2

High-throughput

0.489

High

1389501

OSBL2
Oxysterol-binding protein-related protein 2

1

1

High-throughput

0.489

High

1389503

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

6

High-throughput

0.489

High

1389505

ARP8
Actin-related protein 8

1

12

High-throughput

0.489

High

1389507

Z286A
Zinc finger protein 286A

1

7

High-throughput

0.489

High

1389514

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

4

High-throughput

0.489

High

1389515

CHMP5
Charged multivesicular body protein 5

1

5

High-throughput

0.489

High

1389516

WDR35
WD repeat-containing protein 35

1

11

High-throughput

0.489

High

1389517

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

1

High-throughput

0.489

High

1389519

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

4

High-throughput

0.489

High

1389522

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

10

High-throughput

0.489

High

1389524

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.489

High

1389527

KLDC2
Kelch domain-containing protein 2

1

10

High-throughput

0.489

High

1389529

TLN1
Talin-1

1

11

High-throughput

0.489

High

1389530

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

8

High-throughput

0.489

High

1389531

TLN2
Talin-2

1

12

High-throughput

0.489

High

1389535

MORC2
ATPase MORC2

1

3

High-throughput

0.489

High

942819

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

10

High-throughput

0.479

High

1389498

DDX24
ATP-dependent RNA helicase DDX24

1

12

High-throughput

0.479

High

65795

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

2

High-throughput

0.470

High

46374

A0A1U9X8X8
Corneodesmosin

1

3

High-throughput

0.470

High

63347

A5D903
PRB1 protein

1

7

High-throughput

0.470

High

516030

CSH1
Chorionic somatomammotropin hormone 1

1

1

High-throughput

0.470

High

1045037

PRB3
Basic salivary proline-rich protein 3

1

14

High-throughput

0.470

High

1165250

Q17RA0
Interleukin-6 receptor subunit beta

1

6

High-throughput

0.470

High

1207289

PAGE3
P antigen family member 3

1

2

High-throughput

0.470

High

404872

PRIO
Major prion protein

1

3

High-throughput

0.445

High

407920

PRP1
Basic salivary proline-rich protein 1

1

15

High-throughput

0.439

High

519015

PRB4
Basic salivary proline-rich protein 4

1

13

High-throughput

0.439

High

1149537

CDSN
Corneodesmosin

1

3

High-throughput

0.439

High

1277997

R144B
E3 ubiquitin-protein ligase RNF144B

1

8

High-throughput

0.439

High

106445

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1365486

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

3

High-throughput

0.437

High

1389534

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

11

High-throughput

0.437

High

3230

A0A0S2Z3K0
Collagen type I alpha 2 isoform 5

1

4

High-throughput

0.417

High

108087

G3V529
ATP-dependent RNA helicase

1

13

High-throughput

0.407

High

116948

J3KNB8
Mitogen-activated protein kinase kinase kinase 4

1

10

High-throughput

0.407

High

231513

ORC4
Origin recognition complex subunit 4

1

2

High-throughput

0.407

High

1389533

RAI2
Retinoic acid-induced protein 2

3

0

High-throughput

0.357

High

252220

ISK4
Serine protease inhibitor Kazal-type 4

2

0

High-throughput

0.316

High

336299

DEXI
Dexamethasone-induced protein

2

0

High-throughput

0.316

High

377140

LSHB
Lutropin subunit beta

2

0

High-throughput

0.316

High

407202

CD3D
T-cell surface glycoprotein CD3 delta chain

2

0

High-throughput

0.316

High

1157303

PROL4
Proline-rich protein 4

2

0

High-throughput

0.316

High

1159404

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.316

High

1249772

TM108
Transmembrane protein 108

2

0

High-throughput

0.316

High

1280289

ADAT2
tRNA-specific adenosine deaminase 2

2

0

High-throughput

0.316

High

1350784

MO2R1
Cell surface glycoprotein CD200 receptor 1

2

0

High-throughput

0.316

High

1359853

SELM
Selenoprotein M

2

0

High-throughput

0.316

High

1389523

MUCEN
Endomucin

2

0

High-throughput

0.316

High

1240760

PMF1
Polyamine-modulated factor 1

2

0

High-throughput

0.305

High

219214

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low

276853

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.279

Low

369077

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.279

Low

568469

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

1129563

ESPL1
Separin

1

0

High-throughput

0.279

Low

1156657

UAP1
UDP-N-acetylhexosamine pyrophosphorylase

1

0

High-throughput

0.279

Low

1259056

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low

1278622

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

1383594

K1143
Uncharacterized protein KIAA1143

1

0

High-throughput

0.279

Low

1384674

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.279

Low

1389506

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1389513

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.279

Low

1389528

RRP15
RRP15-like protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025