HitPredict

Interactor 1: PHLP2 (Q6ZVD8)
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)
Gene: PHLPP2

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27880917
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1323 Hs			1 365
+	Hs
		233024 PHLP1_HUMAN (36-1300): 0: 845: 53.04		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		233003 PHLP1_HUMAN (36-1300): 0: 845: 53.04		Q9P1S2_HUMAN (28-187): 2e-55: 180: 95.63
+	Hs
		232821 PHLP1_HUMAN (36-1300): 0: 845: 53.04		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		232984 PHLP1_HUMAN (36-1300): 0: 845: 53.04		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		1357816 SHOC2_HUMAN (251-624): 1.1e-23: 109: 26.84		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1334127 LRC40_HUMAN (249-701): 1.53e-22: 105: 27.03		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1312326 LRRC1_HUMAN (513-772): 7.92e-14: 77.8: 29.83		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1050095 SCRIB_HUMAN (438-732): 2.62e-12: 73.9: 29.00		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1301469 ERBIN_HUMAN (461-746): 7.29e-10: 65.9: 24.75		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73193 SHOC2_HUMAN (251-624): 1.1e-23: 109: 26.84		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73181 LRC40_HUMAN (249-701): 1.53e-22: 105: 27.03		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73173 LRRC1_HUMAN (513-772): 7.92e-14: 77.8: 29.83		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Dm
		1364726 SUR8_DROME (250-660): 2.79e-23: 108: 26.99		Q9VH81_DROME (4-218): 1.63e-39: 148: 13.58
+	Sc
		443957 CYAA_YEAST (624-943): 4.85e-13: 76.3: 15.36		SGT1_YEAST (12-365): 5.06e-48: 168: 24.87
+	Hs
		858664 LRRC1_HUMAN (513-772): 7.92e-14: 77.8: 29.83		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		175307 SHOC2_HUMAN (251-624): 1.1e-23: 109: 26.84		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		174879 SCRIB_HUMAN (438-732): 2.62e-12: 73.9: 29.00		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51