Interactor 1: Q24216 (Q24216)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 7)
Gene: Cdk7

Interactor 2: Q7KPG8 (Q7KPG8)
CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1)
Gene: Mat1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 27183194, 16940351, 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAT1~Pkinase
Common GO terms GO:0005675 - transcription factor TFIIH holo complex
GO:0032806 - carboxy-terminal domain protein kinase complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 353
Dm

1 320
+ Hs
+ Hs
+ Sc
+ Sp
+ At
+ At
+ At

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Last updated: 11Aug2025