Interactor 1: RGMC (Q6ZVN8)
Hemojuvelin (Hemochromatosis type 2 protein) (Hemojuvelin BMP coreceptor) (RGM domain family member C)
Gene: HJV

Interactor 2: TMPS6 (Q8IU80)
Transmembrane protease serine 6 (EC 3.4.21.-) (Matriptase-2)
Gene: TMPRSS6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.55 0.622

The method score is based on:

Property Details
Experiments 18976966, 20704562, 19357398
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0030509 - BMP signaling pathway
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024