HitPredict

Interactor 1: BBS12 (Q6ZW61)
Bardet-Biedl syndrome 12 protein
Gene: BBS12

Interactor 2: MKKS (Q9NPJ1)
Molecular chaperone MKKS (Bardet-Biedl syndrome 6 protein) (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin)
Gene: MKKS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.922

Property	Details
Experiments	28514442, 33961781, 20080638, 26900326, 22500027
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0045444 - fat cell differentiation GO:0045494 - photoreceptor cell maintenance GO:0051131 - chaperone-mediated protein complex assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 570
+	Hs
		826731 BBS12_HUMAN (1-710): 0: 1490: 100.00		TCPG_HUMAN (4-519): 7.61e-164: 479: 19.05
+	Hs
		821280 BBS12_HUMAN (1-710): 0: 1490: 100.00		TCPE_HUMAN (1-516): 2.95e-162: 475: 15.54
+	Hs
		843257 BBS12_HUMAN (1-710): 0: 1490: 100.00		TCPD_HUMAN (19-515): 4.97e-153: 451: 18.65