Protein: TBB2B
Tubulin beta-2B chain

Gene: TBB2B, TUBB2B
Organism: Homo sapiens
Interactions: 234
UniProt ID: Q9BVA1

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000278 - mitotic cell cycle
GO:0001764 - neuron migration
GO:0003924 - GTPase activity
GO:0005200 - structural constituent of cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932127

EPHA4
Ephrin type-A receptor 4

4

11

High-throughput

0.899

High

882130

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.861

High

1007245

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.861

High

1108687

TBB3
Tubulin beta-3 chain

3

16

High-throughput

0.861

High

1191960

TBB8
Tubulin beta-8 chain

3

17

High-throughput

0.861

High

1415112

TBB1
Tubulin beta-1 chain

3

17

High-throughput

0.861

High

997488

TBB4B
Tubulin beta-4B chain

2

15

High-throughput

0.811

High

821544

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.789

High

1259471

TBA1A
Tubulin alpha-1A chain

2

20

High-throughput

0.737

High

63022

POTEF
POTE ankyrin domain family member F

1

8

High-throughput

0.691

High

996834

TBA1B
Tubulin alpha-1B chain

1

20

High-throughput

0.691

High

1118580

TBB2A
Tubulin beta-2A chain

1

15

High-throughput

0.691

High

134957

EMAL1
Echinoderm microtubule-associated protein-like 1

3

20

High-throughput

0.667

High

348914

EMAL2
Echinoderm microtubule-associated protein-like 2

3

20

High-throughput

0.667

High

783121

ARL2
ADP-ribosylation factor-like protein 2

3

11

High-throughput

0.667

High

1413735

TBCD
Tubulin-specific chaperone D

3

5

High-throughput

0.667

High

1415119

EMAL4
Echinoderm microtubule-associated protein-like 4

3

20

High-throughput

0.667

High

1415126

T11L1
T-complex protein 11-like protein 1

3

9

High-throughput

0.667

High

1388566

SACA9
Sperm acrosome-associated protein 9

1

0

High-throughput

0.656

High

1252045

EMAL6
Echinoderm microtubule-associated protein-like 6

2

20

High-throughput

0.628

High

457664

TBB5
Tubulin beta chain

1

16

High-throughput

0.618

High

1026771

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

20

High-throughput

0.618

High

1255342

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1407543

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.618

High

1415135

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.618

High

675139

TNR6
Tumor necrosis factor receptor superfamily member 6

3

16

High-throughput

0.609

High

1119425

CAYP1
Calcyphosin

3

11

High-throughput

0.609

High

1322489

TTC5
Tetratricopeptide repeat protein 5

3

6

High-throughput

0.609

High

1335491

SEN2
tRNA-splicing endonuclease subunit Sen2

2

0

High-throughput

0.585

High

242785

PRKN
E3 ubiquitin-protein ligase parkin

2

18

High-throughput

0.584

High

373031

MYC
Myc proto-oncogene protein

2

9

High-throughput

0.584

High

1415141

TRAF6
TNF receptor-associated factor 6

2

20

Small-scale

0.584

High

944061

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.575

High

139743

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

8

High-throughput

0.573

High

1415130

HDAC6
Protein deacetylase HDAC6

1

16

Small-scale

0.573

High

835743

KPCI
Protein kinase C iota type

2

20

High-throughput

0.571

High

1096493

PAK1
Serine/threonine-protein kinase PAK 1

2

15

High-throughput

0.571

High

1363688

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.553

High

1415113

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.553

High

530314

TAU
Microtubule-associated protein tau

2

15

High-throughput

0.552

High

1006100

DLG4
Disks large homolog 4

1

9

High-throughput

0.541

High

1361829

RSPH1
Radial spoke head 1 homolog

1

5

High-throughput

0.541

High

165724

PPE1
Serine/threonine-protein phosphatase with EF-hands 1

1

10

High-throughput

0.536

High

348703

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

5

High-throughput

0.536

High

461886

HS90A
Heat shock protein HSP 90-alpha

1

6

Small-scale

0.536

High

727945

DNJA1
DnaJ homolog subfamily A member 1

1

16

High-throughput

0.536

High

762160

CNR2
Cannabinoid receptor 2

1

5

Small-scale

0.536

High

909170

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.536

High

984259

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

11

High-throughput

0.536

High

1025839

BORG5
Cdc42 effector protein 1

1

2

High-throughput

0.536

High

1050527

UBE3A
Ubiquitin-protein ligase E3A

1

12

High-throughput

0.536

High

1114178

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1181497

EMAL3
Echinoderm microtubule-associated protein-like 3

1

20

High-throughput

0.536

High

1347858

RIN3
Ras and Rab interactor 3

1

6

High-throughput

0.536

High

1362001

RFFL
E3 ubiquitin-protein ligase rififylin

1

4

High-throughput

0.536

High

1366807

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

3

High-throughput

0.536

High

1371161

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

1

High-throughput

0.536

High

1405022

NEUR1
Sialidase-1

1

1

High-throughput

0.536

High

1415105

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1415107

PRD14
PR domain zinc finger protein 14

1

5

High-throughput

0.536

High

1415111

RBSK
Ribokinase

1

1

High-throughput

0.536

High

1415139

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

1

High-throughput

0.536

High

1415143

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

1

1

High-throughput

0.536

High

1415122

PRDM7
Histone-lysine N-methyltransferase PRDM7

1

3

High-throughput

0.515

High

1415140

DTNA
Dystrobrevin alpha

1

4

High-throughput

0.515

High

1237827

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

20

High-throughput

0.514

High

954601

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.513

High

1037621

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

1136942

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.513

High

1309284

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

0

High-throughput

0.513

High

1395171

ZN333
Zinc finger protein 333

1

0

High-throughput

0.513

High

1409653

CND3
Condensin complex subunit 3

1

0

High-throughput

0.513

High

1415128

AKA7G
A-kinase anchor protein 7 isoform gamma

1

0

High-throughput

0.513

High

628016

ANXA7
Annexin A7

1

2

High-throughput

0.508

High

808161

CDN1A
Cyclin-dependent kinase inhibitor 1

1

2

High-throughput

0.508

High

995237

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.508

High

185982

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

13

High-throughput

0.501

High

139080

LAD1
Ladinin-1

1

2

High-throughput

0.489

High

182358

WDR46
WD repeat-containing protein 46

1

20

High-throughput

0.489

High

346706

NDST3
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

1

1

High-throughput

0.489

High

438908

CD1A
T-cell surface glycoprotein CD1a

1

2

High-throughput

0.489

High

628918

TRYB2
Tryptase beta-2

1

15

High-throughput

0.489

High

1060913

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

5

High-throughput

0.489

High

1177192

MICB
MHC class I polypeptide-related sequence B

1

4

High-throughput

0.489

High

1216358

ZC21B
Zinc finger C2HC domain-containing protein 1B

1

7

High-throughput

0.489

High

1219743

ZMYM4
Zinc finger MYM-type protein 4

1

6

High-throughput

0.489

High

1290380

MOGT3
2-acylglycerol O-acyltransferase 3

1

1

High-throughput

0.489

High

1292405

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

5

High-throughput

0.489

High

1351584

MIPT3
TRAF3-interacting protein 1

1

5

Small-scale

0.489

High

1361865

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

15

High-throughput

0.489

High

1415109

UN93B
Protein unc-93 homolog B1

1

3

High-throughput

0.489

High

1415136

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.489

High

833431

RGS2
Regulator of G-protein signaling 2

1

0

High-throughput

0.486

High

842508

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.486

High

1259019

CENPU
Centromere protein U

1

0

High-throughput

0.486

High

278957

PEX14
Peroxisomal membrane protein PEX14

1

8

Small-scale

0.484

High

138295

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

5

High-throughput

0.479

High

167967

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

16

High-throughput

0.479

High

187402

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

4

High-throughput

0.479

High

214018

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

7

High-throughput

0.479

High

214458

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

20

High-throughput

0.479

High

260398

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

272434

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

276793

TBCA
Tubulin-specific chaperone A

1

3

High-throughput

0.479

High

294273

CD123
Translation initiation factor eIF2 assembly protein

1

6

High-throughput

0.479

High

320030

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

325086

HEXI1
Protein HEXIM1

1

7

High-throughput

0.479

High

341137

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

370773

FOS
Protein c-Fos

1

8

High-throughput

0.479

High

414535

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

471218

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

473036

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

4

High-throughput

0.479

High

488547

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

11

Small-scale

0.479

High

535479

BIP
Endoplasmic reticulum chaperone BiP

1

15

High-throughput

0.479

High

565467

ITA4
Integrin alpha-4

1

6

High-throughput

0.479

High

630024

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

696390

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

756040

MCM5
DNA replication licensing factor MCM5

1

12

High-throughput

0.479

High

831352

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

853731

MK08
Mitogen-activated protein kinase 8

1

9

High-throughput

0.479

High

861754

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

12

Small-scale

0.479

High

888298

MCM2
DNA replication licensing factor MCM2

1

13

High-throughput

0.479

High

907562

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

7

High-throughput

0.479

High

930041

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

10

High-throughput

0.479

High

971015

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

971947

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.479

High

976526

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.479

High

983960

RBX1
E3 ubiquitin-protein ligase RBX1

1

4

High-throughput

0.479

High

1033766

PO5F1
POU domain, class 5, transcription factor 1

1

7

High-throughput

0.479

High

1045716

TF65
Transcription factor p65

1

18

High-throughput

0.479

High

1098838

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

16

High-throughput

0.479

High

1100324

TIF1B
Transcription intermediary factor 1-beta

1

18

High-throughput

0.479

High

1125209

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

18

High-throughput

0.479

High

1135079

CUL7
Cullin-7

1

6

High-throughput

0.479

High

1136345

EMC2
ER membrane protein complex subunit 2

1

12

High-throughput

0.479

High

1138583

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1141603

OZF
Zinc finger protein OZF

1

1

High-throughput

0.479

High

1153107

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

5

High-throughput

0.479

High

1156588

CCDC6
Coiled-coil domain-containing protein 6

1

3

High-throughput

0.479

High

1180252

SMU1
WD40 repeat-containing protein SMU1

1

20

High-throughput

0.479

High

1194347

LARP7
La-related protein 7

1

10

High-throughput

0.479

High

1218652

OTU1
Ubiquitin thioesterase OTU1

1

4

High-throughput

0.479

High

1271834

MEPCE
7SK snRNA methylphosphate capping enzyme

1

7

High-throughput

0.479

High

1291573

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.479

High

1313391

SMC5
Structural maintenance of chromosomes protein 5

1

8

High-throughput

0.479

High

1334861

SERB1
SERPINE1 mRNA-binding protein 1

1

6

High-throughput

0.479

High

1364236

TOPB1
DNA topoisomerase 2-binding protein 1

1

5

High-throughput

0.479

High

1364568

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

11

High-throughput

0.479

High

1369260

RPGR
X-linked retinitis pigmentosa GTPase regulator

1

7

High-throughput

0.479

High

1369577

ATOH1
Transcription factor ATOH1

1

2

Small-scale

0.479

High

1388635

SPDLY
Protein Spindly

1

6

High-throughput

0.479

High

1397389

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

1399838

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

2

High-throughput

0.479

High

1403647

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

15

Small-scale

0.479

High

1407235

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

15

High-throughput

0.479

High

1414719

MET22
Methyltransferase-like protein 22

1

20

High-throughput

0.479

High

1414954

CP250
Centrosome-associated protein CEP250

1

6

High-throughput

0.479

High

1415106

TRI31
E3 ubiquitin-protein ligase TRIM31

1

19

High-throughput

0.479

High

1415108

SPRTN
DNA-dependent metalloprotease SPRTN

1

6

High-throughput

0.479

High

1415110

GAN
Gigaxonin

1

6

High-throughput

0.479

High

1415114

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1415116

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1415121

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.479

High

1415123

FBX6
F-box only protein 6

1

4

High-throughput

0.479

High

1415125

C42S2
CDC42 small effector protein 2

1

2

High-throughput

0.479

High

1415129

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

11

High-throughput

0.479

High

1415131

APC4
Anaphase-promoting complex subunit 4

1

1

Small-scale

0.479

High

1415134

FAF1
FAS-associated factor 1

1

5

High-throughput

0.479

High

1415138

NINL
Ninein-like protein

1

13

High-throughput

0.479

High

1415142

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

20

High-throughput

0.479

High

640616

MK
Midkine

1

0

Small-scale

0.458

High

1063584

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.458

High

1415120

MYO10
Unconventional myosin-X

1

1

Small-scale

0.457

High

1209605

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

13

Small-scale

0.457

High

1415124

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

1415132

TNIK
TRAF2 and NCK-interacting protein kinase

1

10

High-throughput

0.457

High

248239

NDK8
Putative nucleoside diphosphate kinase

1

6

High-throughput

0.445

High

294750

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.445

High

430308

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

564323

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.445

High

935081

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.445

High

1103358

CTBP1
C-terminal-binding protein 1

1

7

High-throughput

0.445

High

1119287

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

8

High-throughput

0.445

High

1415118

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.445

High

1415127

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.445

High

168897

PLD2
Phospholipase D2

1

2

High-throughput

0.437

High

273364

NPHP4
Nephrocystin-4

1

7

High-throughput

0.437

High

412542

NTRK1
High affinity nerve growth factor receptor

1

15

High-throughput

0.437

High

418403

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

560504

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.437

High

576681

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

5

High-throughput

0.437

High

622674

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

16

High-throughput

0.437

High

630348

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

15

High-throughput

0.437

High

651427

CBL
E3 ubiquitin-protein ligase CBL

1

8

High-throughput

0.437

High

693074

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

711407

SHC1
SHC-transforming protein 1

1

19

High-throughput

0.437

High

769059

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

879423

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

914214

EFNA3
Ephrin-A3

1

15

High-throughput

0.437

High

948926

CD81
CD81 antigen

1

6

High-throughput

0.437

High

1031523

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.437

High

1047476

K1C17
Keratin, type I cytoskeletal 17

1

1

High-throughput

0.437

High

1138004

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.437

High

1229066

RNF43
E3 ubiquitin-protein ligase RNF43

1

12

High-throughput

0.437

High

1241945

FBX42
F-box only protein 42

1

1

High-throughput

0.437

High

1271403

KCTD9
BTB/POZ domain-containing protein KCTD9

1

15

High-throughput

0.437

High

1308201

PLD3
5'-3' exonuclease PLD3

1

2

High-throughput

0.437

High

1314394

SLX4
Structure-specific endonuclease subunit SLX4

1

8

High-throughput

0.437

High

1324173

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.437

High

1326893

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.437

High

1330606

PLD5
Inactive phospholipase D5

1

2

High-throughput

0.437

High

1339685

TNIP2
TNFAIP3-interacting protein 2

1

4

High-throughput

0.437

High

1340801

COP1
E3 ubiquitin-protein ligase COP1

1

20

High-throughput

0.437

High

1348200

TIP
T-cell immunomodulatory protein

1

2

High-throughput

0.437

High

1361048

ASB17
Ankyrin repeat and SOCS box protein 17

1

3

High-throughput

0.437

High

1405240

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

20

High-throughput

0.437

High

1415133

ALK
ALK tyrosine kinase receptor

1

14

High-throughput

0.437

High

1120

SIM26
Small integral membrane protein 26

1

3

High-throughput

0.407

High

255196

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.407

High

653546

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.407

High

1249714

CLC4G
C-type lectin domain family 4 member G

1

6

Small-scale

0.407

High

1335703

MOT11
Monocarboxylate transporter 11

1

7

High-throughput

0.407

High

1400126

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

5

High-throughput

0.407

High

1415137

ITM2B
Integral membrane protein 2B

1

10

High-throughput

0.407

High

1194795

GRPL2
GLIPR1-like protein 2

1

0

High-throughput

0.279

Low

1200302

FBLN7
Fibulin-7

1

0

High-throughput

0.279

Low

1203785

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1218858

GP107
Protein GPR107

1

0

High-throughput

0.279

Low

1272151

ARMX6
Protein ARMCX6

1

0

High-throughput

0.279

Low

1322694

CPXCR
CPX chromosomal region candidate gene 1 protein

1

0

High-throughput

0.279

Low

1322719

F177A
Protein FAM177A1

1

0

High-throughput

0.279

Low

1415117

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

939649

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.265

Low

1415115

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025