HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: KDM4C (Q9H3R0)
Lysine-specific demethylase 4C (EC 1.14.11.66) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C) ([histone H3]-trimethyl-L-lysine(9) demethylase 4C)
Gene: KDM4C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21575637
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1056
+	Hs
		935232 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4C_HUMAN (1-1056): 0: 1153: 100.00
+	Hs
		256961 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4A_HUMAN (3-1045): 0: 1036: 52.36
+	Hs
		256973 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM4A_HUMAN (3-1045): 0: 1036: 52.36
+	Hs
		301134 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4B_HUMAN (4-1051): 0: 1024: 51.97
+	Hs
		876688 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		BRPF1_HUMAN (458-904): 4.27e-93: 324: 22.34
+	Hs
		876700 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		BRPF1_HUMAN (458-904): 4.27e-93: 324: 22.34
+	Dm
		356067 H3_DROME (1-136): 3.73e-61: 186: 100.00		TRX_DROME (329-1014): 5.89e-86: 308: 12.50
+	Hs
		934879 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		JADE1_HUMAN (540-929): 3.44e-86: 298: 18.85
+	Hs
		1152679 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		JADE1_HUMAN (540-929): 3.44e-86: 298: 18.85
+	Hs
		935056 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		JADE3_HUMAN (548-923): 7.36e-85: 294: 21.52
+	Hs
		1086246 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		JADE3_HUMAN (548-923): 7.36e-85: 294: 21.52
+	Hs
		319165 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		BRD1_HUMAN (543-871): 2.2e-74: 269: 23.84
+	Hs
		319213 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		BRD1_HUMAN (543-871): 2.2e-74: 269: 23.84
+	Hs
		319242 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		BRD1_HUMAN (543-871): 2.2e-74: 269: 23.84
+	Hs
		782353 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM5C_HUMAN (1-76): 2.43e-15: 83.5: 28.95
+	Hs
		1086304 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM5D_HUMAN (1-119): 1.91e-14: 80.4: 21.01
+	Hs
		666522 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM5A_HUMAN (1-58): 3.52e-13: 76.5: 25.86
+	Hs
		935339 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM5B_HUMAN (9-76): 3.19e-13: 76.5: 29.41
+	Hs
		666535 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM5A_HUMAN (1-58): 3.52e-13: 76.5: 25.86
+	Hs
		666539 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM5A_HUMAN (1-58): 3.52e-13: 76.5: 25.86