Protein: NKRF
NF-kappa-B-repressing factor (NFkB-repressing factor) (NRF) (Protein ITBA4)

Gene: NKRF
Organism: Homo sapiens
Interactions: 240
UniProt ID: O15226

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001671 - ATPase activator activity
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

172314

DHX15
ATP-dependent RNA helicase DHX15

3

1

High-throughput

0.836

High

172320

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

5

7

High-throughput

0.717

High

172425

DHX9
ATP-dependent RNA helicase A

1

2

High-throughput

0.691

High

172523

DDX21
Nucleolar RNA helicase 2

1

2

High-throughput

0.691

High

172328

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

4

7

High-throughput

0.684

High

172494

DHX58
ATP-dependent RNA helicase DHX58

1

5

High-throughput

0.677

High

172411

RED1
Double-stranded RNA-specific editase 1

3

3

High-throughput

0.665

High

172353

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.656

High

172452

IF16
Gamma-interferon-inducible protein 16

3

2

High-throughput

0.656

High

172511

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

3

1

High-throughput

0.656

High

172517

XRN2
5'-3' exoribonuclease 2

3

2

High-throughput

0.656

High

172329

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.640

High

172533

ZN346
Zinc finger protein 346

3

0

High-throughput

0.636

High

172338

NPM
Nucleophosmin

2

1

High-throughput

0.628

High

172400

RS6
Small ribosomal subunit protein eS6

3

0

High-throughput

0.628

High

172429

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.618

High

172443

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.618

High

172460

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.618

High

172467

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.618

High

172508

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.618

High

172430

ILF3
Interleukin enhancer-binding factor 3

2

2

High-throughput

0.611

High

172368

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.602

High

172413

RL19
Large ribosomal subunit protein eL19

2

0

High-throughput

0.602

High

172449

OASL
2'-5'-oligoadenylate synthase-like protein

2

0

High-throughput

0.602

High

172519

LN28A
Protein lin-28 homolog A

2

3

High-throughput

0.601

High

172431

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.586

High

172404

RL31
Large ribosomal subunit protein eL31

2

0

High-throughput

0.585

High

172315

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

172318

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

172343

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

4

Small-scale

0.584

High

172382

YAP1
Transcriptional coactivator YAP1

2

2

Small-scale

0.584

High

172455

LARP7
La-related protein 7

2

2

High-throughput

0.584

High

172331

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

172522

ANLN
Anillin

2

0

High-throughput

0.559

High

172337

JUN
Transcription factor Jun

1

1

High-throughput

0.554

High

171706

WDR46
WD repeat-containing protein 46

1

1

High-throughput

0.536

High

172312

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.536

High

172321

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

172339

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.536

High

172345

H2A1
Histone H2A type 1

1

1

High-throughput

0.536

High

172348

H14
Histone H1.4

1

3

High-throughput

0.536

High

172358

H1T
Histone H1t

1

3

High-throughput

0.536

High

172359

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

172363

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

4

High-throughput

0.536

High

172377

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.536

High

172379

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

172389

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.536

High

172392

FOXL2
Forkhead box protein L2

1

1

High-throughput

0.536

High

172407

RACK1
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.536

High

172410

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.536

High

172412

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

172414

SRSF3
Serine/arginine-rich splicing factor 3

1

5

High-throughput

0.536

High

172417

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

172420

H11
Histone H1.1

1

3

High-throughput

0.536

High

172424

SRSF1
Serine/arginine-rich splicing factor 1

1

4

High-throughput

0.536

High

172433

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.536

High

172434

SRSF6
Serine/arginine-rich splicing factor 6

1

4

High-throughput

0.536

High

172436

CUL1
Cullin-1

1

2

High-throughput

0.536

High

172437

CUL3
Cullin-3

1

2

High-throughput

0.536

High

172451

SRSF7
Serine/arginine-rich splicing factor 7

1

4

High-throughput

0.536

High

172485

PSPC1
Paraspeckle component 1

1

3

High-throughput

0.536

High

172499

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

1

High-throughput

0.536

High

172500

RBM14
RNA-binding protein 14

1

2

High-throughput

0.536

High

172502

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.536

High

172505

RBM4B
RNA-binding protein 4B

1

3

High-throughput

0.536

High

172507

RBM42
RNA-binding protein 42

1

1

High-throughput

0.536

High

172513

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.536

High

172532

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

172535

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

172537

SRPK3
SRSF protein kinase 3

1

2

High-throughput

0.536

High

172540

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.536

High

172542

RBM19
Probable RNA-binding protein 19

1

2

High-throughput

0.536

High

172322

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

172327

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.513

High

172336

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

172341

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

172342

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

172349

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.513

High

172350

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

172354

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

172355

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

0

High-throughput

0.513

High

172371

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

172374

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

172376

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.513

High

172378

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

172380

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

172381

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

172385

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

172386

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

172387

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

172388

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

172393

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.513

High

172394

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

172396

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

172398

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.513

High

172399

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

172403

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

172405

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

172406

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

172435

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

172453

RN151
RING finger protein 151

1

0

High-throughput

0.513

High

172463

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

172466

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

172468

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

172482

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.513

High

172486

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

172490

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

172496

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

172498

ZN668
Zinc finger protein 668

1

0

High-throughput

0.513

High

172526

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

172528

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.513

High

172530

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

172539

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

172356

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

Small-scale

0.501

High

172416

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

3

Small-scale

0.501

High

172422

TF65
Transcription factor p65

1

3

Small-scale

0.501

High

172423

REL
Proto-oncogene c-Rel

1

3

Small-scale

0.501

High

172491

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.501

High

172512

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

4

High-throughput

0.500

High

172375

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

172347

CCL3
C-C motif chemokine 3

1

1

High-throughput

0.489

High

172448

TRBP2
RISC-loading complex subunit TARBP2

1

6

High-throughput

0.481

High

125006

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

172311

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

172313

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

172316

HBP1
HMG box-containing protein 1

1

1

High-throughput

0.479

High

172326

ARI2
E3 ubiquitin-protein ligase ARIH2

1

2

High-throughput

0.479

High

172333

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

172335

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

172344

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

172346

H2AB2
Histone H2A-Bbd type 2/3

1

2

High-throughput

0.479

High

172351

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

172352

GATA1
Erythroid transcription factor

1

1

High-throughput

0.479

High

172360

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

172364

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

172367

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

172370

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

172372

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

172384

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

172390

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.479

High

172427

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

172428

GRSF1
G-rich sequence factor 1

1

7

High-throughput

0.479

High

172432

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.479

High

172440

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

172446

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

172447

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

172450

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

172457

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

172458

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

172462

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

172464

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

172465

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

172469

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

172470

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

172474

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

172477

NUP43
Nucleoporin Nup43

1

5

High-throughput

0.479

High

172484

PHIP
PH-interacting protein

1

3

High-throughput

0.479

High

172489

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

172492

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

1

High-throughput

0.479

High

172495

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

172503

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.479

High

172504

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

172506

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

1

High-throughput

0.479

High

172520

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

172521

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

1

High-throughput

0.479

High

172524

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

172529

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

172536

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

172538

CE164
Centrosomal protein of 164 kDa

1

1

High-throughput

0.479

High

172543

MAFB
Transcription factor MafB

1

1

High-throughput

0.479

High

172544

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

172454

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

3

High-throughput

0.470

High

172509

KIFC1
Kinesin-like protein KIFC1

1

0

High-throughput

0.460

High

122369

MEN1
Menin

1

0

High-throughput

0.458

High

133238

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

172317

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

172323

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

172324

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

172332

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

172340

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

172357

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

172361

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

172365

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

172366

NOS2
Nitric oxide synthase, inducible

1

0

Small-scale

0.458

High

172369

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

172373

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

172383

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

172391

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

172395

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

172401

H4
Histone H4

1

0

High-throughput

0.458

High

172402

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

172408

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.458

High

172409

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

Small-scale

0.458

High

172415

VIGLN
Vigilin

1

0

High-throughput

0.458

High

172418

EXOSX
Exosome complex component 10

1

0

High-throughput

0.458

High

172419

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

172421

HEN1
Helix-loop-helix protein 1

1

0

High-throughput

0.458

High

172438

KLF5
Krueppel-like factor 5

1

0

High-throughput

0.458

High

172444

MTF1
Metal regulatory transcription factor 1

1

0

High-throughput

0.458

High

172445

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

172461

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

172473

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

172475

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

172478

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

172479

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

172481

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

172483

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

172487

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

172493

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

172497

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

172501

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

172515

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

172516

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

172525

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

172527

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

172541

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

172456

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.457

High

172488

ESR2
Estrogen receptor beta

1

3

High-throughput

0.445

High

172330

RASK
GTPase KRas

1

1

High-throughput

0.437

High

172459

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

172518

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

172534

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

172442

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

172472

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

172514

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

172426

LG3BP
Galectin-3-binding protein

3

0

High-throughput

0.352

High

172439

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

172441

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

172531

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

172362

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.265

Low

148146

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

169319

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

172319

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

172334

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

172397

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

172471

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

172476

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

172480

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

172510

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

172325

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024