HitPredict

Interactor 1: MD13L (Q71F56)
Mediator of RNA polymerase II transcription subunit 13-like (Mediator complex subunit 13-like) (Thyroid hormone receptor-associated protein 2) (Thyroid hormone receptor-associated protein complex 240 kDa component-like)
Gene: MED13L

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25281560, 24981860, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016592 - mediator complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2210 Hs			1 1368
+	Hs
		1355586 MED13_HUMAN (4-2210): 0: 3181: 51.34		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Dm
		1182318 MED13_DROME (943-1152): 8.63e-10: 66.7: 23.77		MED23_DROME (1-1336): 0: 1744: 48.34
+	Ce
		1014362 MED13_CAEEL (1105-1455): 4.78e-26: 120: 23.21		MED23_CAEEL (44-1342): 0: 1394: 20.98