HitPredict

Interactor 1: TMED3 (Q78IS1)
Transmembrane emp24 domain-containing protein 3 (p24 family protein gamma-4) (p24gamma4)
Gene: TMED3

Interactor 2: FNDC5 (Q8K4Z2)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) (Peroxisomal protein) (PeP) [Cleaved into: Irisin]
Gene: FNDC5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 221 Mm			1 209
+	Mm
		88386 D3YZZ5_MOUSE (28-221): 3.02e-76: 231: 68.56		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225315 TMED4_MOUSE (13-215): 1.85e-73: 224: 23.74		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225453 TMED9_MOUSE (1-215): 1.25e-72: 222: 22.94		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225751 TMED2_MOUSE (31-215): 2.51e-69: 212: 29.19		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225591 TMEDA_MOUSE (19-215): 8.06e-69: 211: 21.78		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1225552 TMED5_MOUSE (27-214): 1.9e-58: 185: 32.32		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00
+	Mm
		1113415 TMED1_MOUSE (27-217): 3.29e-53: 172: 33.50		FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00