Protein: FRIH
Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed]

Gene: FRIH, FTH1
Organism: Homo sapiens
Interactions: 164
UniProt ID: P02794

Gene Ontology (top 5):
GO:0004322 - ferroxidase activity
GO:0005506 - iron ion binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364816

FRIL
Ferritin light chain

8

16

High-throughput

0.978

High

365121

FRIH
Ferritin heavy chain

3

15

Small-scale

0.833

High

365192

NCOA4
Nuclear receptor coactivator 4

6

2

Small-scale

0.736

High

365173

FXR2
RNA-binding protein FXR2

3

1

High-throughput

0.666

High

198361

KLK10
Kallikrein-10

2

4

High-throughput

0.628

High

207158

TGM5
Protein-glutamine gamma-glutamyltransferase 5

2

2

High-throughput

0.628

High

234172

PEPL
Periplakin

2

1

High-throughput

0.628

High

245774

CATL2
Cathepsin L2

2

1

High-throughput

0.628

High

271848

SPB7
Serpin B7

2

5

High-throughput

0.628

High

344838

CYTS
Cystatin-S

2

3

High-throughput

0.628

High

365124

SEMG1
Semenogelin-1

2

1

High-throughput

0.628

High

365127

INVO
Involucrin

2

2

High-throughput

0.628

High

365147

IL1RA
Interleukin-1 receptor antagonist protein

2

1

High-throughput

0.628

High

365149

FILA
Filaggrin

2

3

High-throughput

0.628

High

365151

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

2

High-throughput

0.628

High

365156

SPB3
Serpin B3

2

5

High-throughput

0.628

High

365168

SPB4
Serpin B4

2

5

High-throughput

0.628

High

365170

KLK7
Kallikrein-7

2

3

High-throughput

0.628

High

365186

SEMG2
Semenogelin-2

2

1

High-throughput

0.628

High

365187

TGM3
Protein-glutamine gamma-glutamyltransferase E

2

2

High-throughput

0.628

High

365242

IL37
Interleukin-37

2

1

High-throughput

0.628

High

365244

CRNN
Cornulin

2

2

High-throughput

0.628

High

365245

KLK11
Kallikrein-11

2

3

High-throughput

0.628

High

365251

KLK5
Kallikrein-5

2

3

High-throughput

0.628

High

365246

DAXX
Death domain-associated protein 6

2

0

Small-scale

0.614

High

365221

TSC1
Hamartin

2

0

Small-scale

0.607

High

259819

LX12B
Arachidonate 12-lipoxygenase, 12R-type

2

0

High-throughput

0.602

High

363376

RET4
Retinol-binding protein 4

2

0

High-throughput

0.602

High

365142

PPAP
Prostatic acid phosphatase

2

0

High-throughput

0.602

High

365158

CASPE
Caspase-14

2

0

High-throughput

0.602

High

365164

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.602

High

365202

PLBL1
Phospholipase B-like 1

2

0

High-throughput

0.602

High

365215

RDHE2
Epidermal retinol dehydrogenase 2

2

0

High-throughput

0.602

High

365232

TREX2
Three prime repair exonuclease 2

2

0

High-throughput

0.602

High

160317

AURKA
Aurora kinase A

2

3

High-throughput

0.584

High

365226

AURKB
Aurora kinase B

2

3

High-throughput

0.584

High

365126

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.582

High

313989

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

365179

MAX
Protein max

1

6

High-throughput

0.578

High

132708

SDCB1
Syntenin-1

2

3

High-throughput

0.576

High

365227

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

2

High-throughput

0.576

High

365210

SPA12
Serpin A12

2

4

High-throughput

0.574

High

365247

CBPA4
Carboxypeptidase A4

2

3

High-throughput

0.574

High

319688

HERC2
E3 ubiquitin-protein ligase HERC2

2

1

High-throughput

0.571

High

365195

PCBP1
Poly(rC)-binding protein 1

1

2

Small-scale

0.561

High

365196

PCBP2
Poly(rC)-binding protein 2

1

2

Small-scale

0.561

High

66369

A2ML1
Alpha-2-macroglobulin-like protein 1

2

1

High-throughput

0.552

High

365130

MYL3
Myosin light chain 3

1

1

High-throughput

0.541

High

365172

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

365185

DLG4
Disks large homolog 4

1

1

High-throughput

0.541

High

365225

OPTN
Optineurin

1

2

High-throughput

0.541

High

365184

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

0

Small-scale

0.537

High

279395

FLOT1
Flotillin-1

1

3

High-throughput

0.536

High

344914

CYTN
Cystatin-SN

1

3

High-throughput

0.536

High

365128

YES
Tyrosine-protein kinase Yes

1

2

High-throughput

0.536

High

365129

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.536

High

365133

RAP2A
Ras-related protein Rap-2a

1

2

High-throughput

0.536

High

365141

CBPM
Carboxypeptidase M

1

3

High-throughput

0.536

High

365155

CALL3
Calmodulin-like protein 3

1

1

High-throughput

0.536

High

365161

SPB5
Serpin B5

1

5

High-throughput

0.536

High

365166

MK09
Mitogen-activated protein kinase 9

1

1

High-throughput

0.536

High

365188

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.536

High

365197

CYTM
Cystatin-M

1

3

High-throughput

0.536

High

365200

FILA2
Filaggrin-2

1

3

High-throughput

0.536

High

365222

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.536

High

365229

CPNS2
Calpain small subunit 2

1

2

High-throughput

0.536

High

365243

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.536

High

365248

SPB13
Serpin B13

1

4

High-throughput

0.536

High

365253

RAP2C
Ras-related protein Rap-2c

1

2

High-throughput

0.536

High

365254

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.536

High

72269

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

2

1

High-throughput

0.533

High

365157

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.518

High

365160

SOX5
Transcription factor SOX-5

1

0

High-throughput

0.518

High

365193

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.518

High

365211

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.518

High

365234

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

0

High-throughput

0.518

High

365236

TOLIP
Toll-interacting protein

1

0

High-throughput

0.518

High

365238

ELL3
RNA polymerase II elongation factor ELL3

1

0

High-throughput

0.518

High

365240

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.518

High

224744

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.513

High

274061

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

365138

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

365139

PLSL
Plastin-2

1

0

High-throughput

0.513

High

365144

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.513

High

365145

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.513

High

365150

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.513

High

365153

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.513

High

365154

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

365165

MATR3
Matrin-3

1

0

High-throughput

0.513

High

365167

MAOX
NADP-dependent malic enzyme

1

0

High-throughput

0.513

High

365180

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

365191

ASAH1
Acid ceramidase

1

0

High-throughput

0.513

High

365199

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.513

High

365203

SBSN
Suprabasin

1

0

High-throughput

0.513

High

365205

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

365212

MSRB3
Methionine-R-sulfoxide reductase B3

1

0

High-throughput

0.513

High

365231

GSDMA
Gasdermin-A

1

0

High-throughput

0.513

High

365250

GUAD
Guanine deaminase

1

0

High-throughput

0.513

High

365256

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.513

High

365152

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

1

High-throughput

0.500

High

364124

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.494

High

365239

GPR35
G-protein coupled receptor 35

1

1

High-throughput

0.494

High

365252

LC7L2
Putative RNA-binding protein Luc7-like 2

1

2

High-throughput

0.489

High

365123

GCR
Glucocorticoid receptor

1

1

High-throughput

0.481

High

365174

IMA1
Importin subunit alpha-1

1

5

High-throughput

0.481

High

365182

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.481

High

365194

NR1I3
Nuclear receptor subfamily 1 group I member 3

1

1

High-throughput

0.481

High

365233

TRAF4
TNF receptor-associated factor 4

1

1

Small-scale

0.481

High

365163

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.480

High

365177

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

301521

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

345645

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

365122

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

365131

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

365143

VATB1
V-type proton ATPase subunit B, kidney isoform

1

2

High-throughput

0.479

High

365175

PCBP3
Poly(rC)-binding protein 3

1

2

Small-scale

0.479

High

365190

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

365204

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

365207

TAXB1
Tax1-binding protein 1

1

3

High-throughput

0.479

High

365209

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

365220

ASB15
Ankyrin repeat and SOCS box protein 15

1

1

High-throughput

0.479

High

365223

IGSF8
Immunoglobulin superfamily member 8

1

2

High-throughput

0.479

High

365230

ASB16
Ankyrin repeat and SOCS box protein 16

1

2

High-throughput

0.479

High

365235

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

2

High-throughput

0.479

High

365237

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

Small-scale

0.479

High

365255

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

Small-scale

0.479

High

130313

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

0

High-throughput

0.460

High

365134

OSTP
Osteopontin

1

0

Small-scale

0.460

High

365140

CD99
CD99 antigen

1

0

Small-scale

0.460

High

365146

LBP
Lipopolysaccharide-binding protein

1

0

High-throughput

0.460

High

365181

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.460

High

365183

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.460

High

365189

CDC16
Cell division cycle protein 16 homolog

1

0

High-throughput

0.460

High

365214

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.460

High

365125

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

365132

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

365137

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

365148

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

365171

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

365178

CXCR4
C-X-C chemokine receptor type 4

1

0

Small-scale

0.458

High

365198

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

365201

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

365228

SPTCS
Spatacsin

1

1

Small-scale

0.457

High

56590

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.445

High

73203

B4DZ85
Nuclear receptor coactivator 4

1

2

High-throughput

0.445

High

365135

TAU
Microtubule-associated protein tau

1

1

Small-scale

0.445

High

365159

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

365162

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

365216

POC5
Centrosomal protein POC5

1

1

High-throughput

0.445

High

365136

CLUS
Clusterin

1

0

High-throughput

0.438

High

365176

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

365241

NLE1
Notchless protein homolog 1

1

3

High-throughput

0.437

High

353486

IGKC
Immunoglobulin kappa constant

1

0

High-throughput

0.426

High

365219

POF1B
Protein POF1B

2

0

High-throughput

0.328

High

365217

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.282

High

365169

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

365224

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

365249

LTOR2
Ragulator complex protein LAMTOR2

1

0

High-throughput

0.279

Low

365208

TCAM2
TIR domain-containing adapter molecule 2

1

0

High-throughput

0.251

Low

327330

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.249

Low

365213

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

365218

MIPT3
TRAF3-interacting protein 1

1

0

High-throughput

0.238

Low

365206

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024