HitPredict

Interactor 1: MYO1F (O00160)
Unconventional myosin-If (Myosin-Ie)
Gene: MYO1F

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1098 Hs			1 465
+	Hs
		226691 MYH11_HUMAN (5-1000): 0: 1028: 26.48		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226680 MYH10_HUMAN (5-986): 0: 1027: 27.04		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226679 MYH9_HUMAN (5-1000): 0: 1025: 27.34		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227361 MYO7A_HUMAN (7-959): 0: 999: 31.10		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1033097 MYO7A_HUMAN (7-959): 0: 999: 31.10		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	At
		98845 MYO17_ARATH (1-1056): 0: 1074: 28.08		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Hs
		475291 MYH1_HUMAN (4-870): 0: 1029: 30.68		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475417 MYH9_HUMAN (5-1000): 0: 1025: 27.34		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		214436 MYO1B_HUMAN (18-705): 0: 616: 45.78		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		297276 MYO1D_HUMAN (18-741): 5.83e-179: 551: 40.67		UBB_HUMAN (1-234): 1.14e-59: 197: 17.92
+	Hs
		1219401 MYO5A_HUMAN (688-1060): 9.97e-11: 68.6: 9.69		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58