Protein: NSF
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)

Gene: NSF
Organism: Homo sapiens
Interactions: 215
UniProt ID: P46459

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0001921 - positive regulation of receptor recycling
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

803882

SNAA
Alpha-soluble NSF attachment protein

6

9

Small-scale

0.950

High

803963

SNAG
Gamma-soluble NSF attachment protein

3

9

High-throughput

0.871

High

803872

NSF
Vesicle-fusing ATPase

2

19

Small-scale

0.755

High

226786

PRKN
E3 ubiquitin-protein ligase parkin

2

15

High-throughput

0.754

High

212755

STX6
Syntaxin-6

4

7

High-throughput

0.699

High

803970

ASPC1
Tether containing UBX domain for GLUT4

1

8

Small-scale

0.680

High

803944

STX12
Syntaxin-12

3

13

High-throughput

0.675

High

178427

STX7
Syntaxin-7

3

14

High-throughput

0.667

High

369151

ESR1
Estrogen receptor

3

13

Small-scale

0.641

High

803975

RBSK
Ribokinase

3

0

High-throughput

0.634

High

261641

VAMP4
Vesicle-associated membrane protein 4

2

8

High-throughput

0.628

High

309566

GOSR1
Golgi SNAP receptor complex member 1

2

1

High-throughput

0.628

High

803948

SCFD1
Sec1 family domain-containing protein 1

2

4

High-throughput

0.628

High

803994

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

3

High-throughput

0.628

High

803999

STX8
Syntaxin-8

2

9

High-throughput

0.628

High

786722

GRIA2
Glutamate receptor 2

2

3

Small-scale

0.624

High

496520

TAU
Microtubule-associated protein tau

3

6

High-throughput

0.624

High

299330

UBXN7
UBX domain-containing protein 7

1

20

High-throughput

0.618

High

803997

UBQL2
Ubiquilin-2

1

8

High-throughput

0.618

High

803906

STX5
Syntaxin-5

2

17

High-throughput

0.611

High

803910

CUL3
Cullin-3

2

10

High-throughput

0.611

High

169401

BET1
BET1 homolog

3

7

High-throughput

0.599

High

803931

MIDN
Midnolin

1

0

High-throughput

0.586

High

322306

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

5

High-throughput

0.584

High

803881

RAB9A
Ras-related protein Rab-9A

2

7

High-throughput

0.584

High

803891

RHOB
Rho-related GTP-binding protein RhoB

2

15

High-throughput

0.584

High

803901

EP300
Histone acetyltransferase p300

2

6

High-throughput

0.584

High

277384

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

4

Small-scale

0.573

High

803993

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

4

Small-scale

0.561

High

803938

BCOR
BCL-6 corepressor

1

7

High-throughput

0.553

High

117986

SNP23
Synaptosomal-associated protein 23

1

6

High-throughput

0.536

High

123534

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.536

High

149571

COPE
Coatomer subunit epsilon

1

1

High-throughput

0.536

High

151551

GOSR2
Golgi SNAP receptor complex member 2

1

3

High-throughput

0.536

High

152139

STX16
Syntaxin-16

1

12

High-throughput

0.536

High

168353

SCAM1
Secretory carrier-associated membrane protein 1

1

2

High-throughput

0.536

High

168517

SCAM2
Secretory carrier-associated membrane protein 2

1

2

High-throughput

0.536

High

235153

STX10
Syntaxin-10

1

8

High-throughput

0.536

High

263192

SC22B
Vesicle-trafficking protein SEC22b

1

6

High-throughput

0.536

High

306771

VAMP5
Vesicle-associated membrane protein 5

1

9

High-throughput

0.536

High

320275

SNP29
Synaptosomal-associated protein 29

1

6

High-throughput

0.536

High

358727

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.536

High

394301

A4
Amyloid-beta precursor protein

1

2

Small-scale

0.536

High

555233

NQO2
Ribosyldihydronicotinamide dehydrogenase [quinone]

1

1

High-throughput

0.536

High

569059

DESM
Desmin

1

7

High-throughput

0.536

High

699248

STX2
Syntaxin-2

1

15

High-throughput

0.536

High

725382

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.536

High

803874

GNPI1
Glucosamine-6-phosphate isomerase 1

1

1

High-throughput

0.536

High

803880

RAB7A
Ras-related protein Rab-7a

1

6

High-throughput

0.536

High

803889

RAB14
Ras-related protein Rab-14

1

9

High-throughput

0.536

High

803892

RAB1A
Ras-related protein Rab-1A

1

6

High-throughput

0.536

High

803893

VAMP2
Vesicle-associated membrane protein 2

1

10

High-throughput

0.536

High

803894

BT3A2
Butyrophilin subfamily 3 member A2

1

2

High-throughput

0.536

High

803907

STX3
Syntaxin-3

1

14

High-throughput

0.536

High

803923

VAMP3
Vesicle-associated membrane protein 3

1

10

High-throughput

0.536

High

803946

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.536

High

803954

RAB24
Ras-related protein Rab-24

1

5

High-throughput

0.536

High

803955

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

3

High-throughput

0.536

High

803964

GPA33
Cell surface A33 antigen

1

3

High-throughput

0.536

High

803966

VAMP8
Vesicle-associated membrane protein 8

1

6

High-throughput

0.536

High

803969

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

803972

RAB1B
Ras-related protein Rab-1B

1

3

High-throughput

0.536

High

803983

RTN4
Reticulon-4

1

1

High-throughput

0.536

High

803988

BET1L
BET1-like protein

1

6

High-throughput

0.536

High

803992

STX18
Syntaxin-18

1

3

High-throughput

0.536

High

804000

AKT3
RAC-gamma serine/threonine-protein kinase

1

6

High-throughput

0.536

High

400250

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.518

High

803884

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.518

High

127739

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.515

High

562898

STMN1
Stathmin

1

2

High-throughput

0.515

High

803959

SENP8
Sentrin-specific protease 8

1

2

High-throughput

0.515

High

130035

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.513

High

803911

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.513

High

803914

GNMT
Glycine N-methyltransferase

1

0

High-throughput

0.513

High

803917

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.513

High

803921

TSN
Translin

1

0

High-throughput

0.513

High

803952

YIPF5
Protein YIPF5

1

0

High-throughput

0.513

High

803956

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.513

High

803979

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.513

High

804003

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

804005

SALL2
Sal-like protein 2

1

0

High-throughput

0.513

High

804006

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.513

High

796392

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

12

Small-scale

0.512

High

426950

FES
Tyrosine-protein kinase Fes/Fps

1

3

Small-scale

0.501

High

441189

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

9

High-throughput

0.501

High

561385

FER
Tyrosine-protein kinase Fer

1

2

Small-scale

0.501

High

616909

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

10

High-throughput

0.501

High

617088

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

14

High-throughput

0.501

High

803900

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

16

High-throughput

0.501

High

803903

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

11

High-throughput

0.501

High

803919

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

9

High-throughput

0.501

High

803926

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

9

High-throughput

0.501

High

804002

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.494

High

283170

RGS20
Regulator of G-protein signaling 20

1

0

High-throughput

0.493

High

803915

CRYM
Ketimine reductase mu-crystallin

1

0

High-throughput

0.493

High

803974

TPK1
Thiamin pyrophosphokinase 1

1

0

High-throughput

0.493

High

803987

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.493

High

803883

FOXA3
Hepatocyte nuclear factor 3-gamma

1

1

High-throughput

0.489

High

803904

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.489

High

803905

SEC20
Vesicle transport protein SEC20

1

1

High-throughput

0.489

High

803909

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

803961

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.489

High

803971

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.489

High

245320

RAMP3
Receptor activity-modifying protein 3

1

0

Small-scale

0.480

High

119235

LEG9
Galectin-9

1

1

High-throughput

0.479

High

148507

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

205153

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

326496

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

338103

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

348563

RASN
GTPase NRas

1

9

High-throughput

0.479

High

349179

RASH
GTPase HRas

1

6

High-throughput

0.479

High

349956

RASK
GTPase KRas

1

8

High-throughput

0.479

High

384454

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

428961

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.479

High

436194

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

443384

VIME
Vimentin

1

7

High-throughput

0.479

High

495486

THIO
Thioredoxin

1

6

Small-scale

0.479

High

503634

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

506915

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

507903

FGFR1
Fibroblast growth factor receptor 1

1

5

High-throughput

0.479

High

528362

MYH6
Myosin-6

1

1

High-throughput

0.479

High

538784

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

5

High-throughput

0.479

High

564445

RHOQ
Rho-related GTP-binding protein RhoQ

1

16

High-throughput

0.479

High

650605

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

665449

EPHA8
Ephrin type-A receptor 8

1

1

High-throughput

0.479

High

668504

PML
Protein PML

1

6

High-throughput

0.479

High

681727

AKT1
RAC-alpha serine/threonine-protein kinase

1

6

Small-scale

0.479

High

684493

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

718595

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

749202

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

778977

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

803875

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

803877

ARRB1
Beta-arrestin-1

1

1

Small-scale

0.479

High

803879

5HT6R
5-hydroxytryptamine receptor 6

1

2

Small-scale

0.479

High

803886

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

803887

RAB4B
Ras-related protein Rab-4B

1

9

High-throughput

0.479

High

803888

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

803890

RHOA
Transforming protein RhoA

1

15

High-throughput

0.479

High

803895

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

803896

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

803899

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

8

High-throughput

0.479

High

803902

STX4
Syntaxin-4

1

14

High-throughput

0.479

High

803908

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

803916

IMB1
Importin subunit beta-1

1

4

High-throughput

0.479

High

803918

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

803922

RHOH
Rho-related GTP-binding protein RhoH

1

17

High-throughput

0.479

High

803924

NTRK3
NT-3 growth factor receptor

1

8

High-throughput

0.479

High

803925

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.479

High

803927

DUS6
Dual specificity protein phosphatase 6

1

5

High-throughput

0.479

High

803928

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

803929

GRDN
Girdin

1

7

High-throughput

0.479

High

803930

LARP7
La-related protein 7

1

6

High-throughput

0.479

High

803933

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

803936

RICTR
Rapamycin-insensitive companion of mTOR

1

3

High-throughput

0.479

High

803937

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

803940

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

803942

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

803943

WAPL
Wings apart-like protein homolog

1

1

High-throughput

0.479

High

803949

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

803953

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

803960

SCLT1
Sodium channel and clathrin linker 1

1

7

High-throughput

0.479

High

803965

PCGF1
Polycomb group RING finger protein 1

1

5

High-throughput

0.479

High

803973

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

803976

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.479

High

803977

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

803978

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

803981

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.479

High

803982

NEK6
Serine/threonine-protein kinase Nek6

1

7

High-throughput

0.479

High

803984

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

803985

DUS22
Dual specificity protein phosphatase 22

1

4

High-throughput

0.479

High

803990

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

803995

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

803996

TBK1
Serine/threonine-protein kinase TBK1

1

3

High-throughput

0.479

High

804008

KC1G3
Casein kinase I isoform gamma-3

1

6

High-throughput

0.479

High

803934

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

351298

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

803873

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

803897

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

803945

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

804004

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

804007

DJC15
DnaJ homolog subfamily C member 15

1

0

High-throughput

0.458

High

596516

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

2

High-throughput

0.445

High

803885

SNP25
Synaptosomal-associated protein 25

1

6

Small-scale

0.445

High

803898

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

1

High-throughput

0.445

High

803912

BECN1
Beclin-1

1

2

High-throughput

0.445

High

803932

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

803935

PKHA7
Pleckstrin homology domain-containing family A member 7

1

9

High-throughput

0.445

High

804001

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

803878

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

181075

INSI1
Insulin-induced gene 1 protein

1

2

High-throughput

0.437

High

233276

NUPR1
Nuclear protein 1

1

2

High-throughput

0.437

High

303001

HEXI1
Protein HEXIM1

1

2

High-throughput

0.437

High

552167

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

569355

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

654150

CALX
Calnexin

1

4

High-throughput

0.437

High

719909

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

803876

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

803913

RBM39
RNA-binding protein 39

1

5

High-throughput

0.437

High

803939

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

803947

DUS19
Dual specificity protein phosphatase 19

1

5

High-throughput

0.437

High

803950

ESR2
Estrogen receptor beta

1

12

High-throughput

0.437

High

803951

HDAC2
Histone deacetylase 2

1

6

High-throughput

0.437

High

803962

RING2
E3 ubiquitin-protein ligase RING2

1

8

High-throughput

0.437

High

803980

NANOG
Homeobox protein NANOG

1

2

High-throughput

0.437

High

803989

USE1
Vesicle transport protein USE1

1

1

Small-scale

0.407

High

803968

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.282

High

803991

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

803998

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

803957

REEP6
Receptor expression-enhancing protein 6

1

0

High-throughput

0.279

Low

803967

F174C
Protein FAM174C

1

0

High-throughput

0.279

Low

803920

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

803941

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.249

Low

803958

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

803986

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024