HitPredict

Interactor 1: SNP23 (O00161)
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)
Gene: SNAP23

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	9507000, 26186194, 28514442, 33961781, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005654 - nucleoplasm GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 276
+	Hs
		118010 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1B_HUMAN (4-273): 3.79e-67: 212: 23.19
+	Hs
		118037 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1A_HUMAN (17-273): 6.81e-67: 211: 23.19
+	Hs
		117977 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	Rn
		250768 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX1B_RAT (4-273): 3.79e-67: 212: 23.19
+	Mm
		140165 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX1A_MOUSE (18-273): 2.43e-67: 212: 24.05
+	Hs
		117929 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Ce
		183449 O62414_CAEEL (4-209): 2.49e-58: 184: 46.60		STX1A_CAEEL (4-276): 2.41e-67: 212: 23.38
+	Dm
		1098103 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Hs
		118025 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX4_HUMAN (6-272): 1.25e-53: 177: 24.27
+	Hs
		118028 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Rn
		250772 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX4_RAT (6-273): 2.16e-53: 177: 24.91
+	Dm
		739422 SNP25_DROME (6-210): 1.87e-57: 182: 50.24		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	At
		1351792 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY121_ARATH (8-252): 2.96e-59: 193: 18.75
+	Rn
		250771 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX3_RAT (5-250): 1.06e-51: 172: 25.60
+	Mm
		140169 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX3_MOUSE (5-250): 1.46e-51: 172: 25.60
+	Dm
		1178788 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	At
		1114737 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY111_ARATH (4-252): 1.64e-51: 172: 19.77
+	Dm
		1366725 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	Ce
		248220 O62414_CAEEL (4-209): 2.49e-58: 184: 46.60		STX3_CAEEL (22-269): 8.73e-44: 152: 20.64
+	Dm
		1366722 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VR90_DROME (166-256): 7.07e-11: 63.5: 36.26