HitPredict

Interactor 1: Q7KA43 (Q7KA43)
Anaphase-promoting complex subunit 11
Gene: lmgA

Interactor 2: UBE2C (Q9VTY6)
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (Ubiquitin carrier protein C) (Ubiquitin carrier protein vihar) (Ubiquitin-protein ligase C)
Gene: vih

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22417125
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-ANAPC11
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0045842 - positive regulation of mitotic metaphase/anaphase transition
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 85 Dm			1 178
+	Sc
		549847 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		UBC4_YEAST (32-176): 2.9e-78: 231: 36.99
+	Sc
		549868 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		UBC5_YEAST (32-176): 4.49e-77: 228: 37.67
+	Hs
		921482 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2D4_HUMAN (33-176): 1.14e-79: 234: 37.93
+	Hs
		849463 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		UB2D1_HUMAN (33-176): 5.61e-79: 233: 37.24
+	Hs
		919882 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		UB2D2_HUMAN (33-176): 6.05e-79: 233: 37.93
+	Hs
		849303 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2D1_HUMAN (33-176): 5.61e-79: 233: 37.24
+	Mm
		895979 RBX1_MOUSE (2-82): 4.29e-28: 99: 36.05		UB2D1_MOUSE (33-176): 5.61e-79: 233: 37.24
+	Hs
		919703 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2D2_HUMAN (33-176): 6.05e-79: 233: 37.93
+	Mm
		919923 RBX1_MOUSE (2-82): 4.29e-28: 99: 36.05		UB2D2_MOUSE (33-176): 6.05e-79: 233: 37.93
+	Hs
		921392 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2E2_HUMAN (4-176): 2.93e-78: 233: 32.18
+	Ce
		715111 RBX1_CAEEL (2-82): 1.34e-27: 97.9: 36.05		UBC2_CAEEL (33-176): 3.53e-78: 231: 37.24
+	Hs
		895932 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		UB2D3_HUMAN (33-176): 4.02e-77: 228: 37.24
+	Hs
		895771 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2D3_HUMAN (33-176): 4.02e-77: 228: 37.24
+	Mm
		895973 RBX1_MOUSE (2-82): 4.29e-28: 99: 36.05		UB2D3_MOUSE (33-176): 4.02e-77: 228: 37.24
+	Hs
		851800 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2E1_HUMAN (4-176): 3.24e-76: 227: 32.76
+	Mm
		854552 RBX1_MOUSE (2-82): 4.29e-28: 99: 36.05		UB2E3_MOUSE (9-176): 2.32e-75: 226: 32.54
+	Hs
		921379 RBX1_HUMAN (2-82): 4.29e-28: 99: 36.05		UB2E3_HUMAN (9-176): 2.32e-75: 226: 32.54
+	Hs
		135955 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		UBE2C_HUMAN (2-174): 2.05e-70: 212: 56.65
+	Xl
		881719 Q5M7C0_XENLA (1-82): 6.11e-29: 100: 71.95		UBE2C_XENLA (2-174): 3.44e-69: 209: 58.96
+	Sc
		854633 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		UBC11_YEAST (25-177): 3.02e-54: 171: 54.19