Protein: USB1
U6 snRNA phosphodiesterase 1 (hUsb1) (3'-5' RNA exonuclease USB1) (EC 4.6.1.-) (Mutated in poikiloderma with neutropenia protein 1) (Mutated in PN protein 1) (hMpn1)

Gene: USB1
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q9BQ65

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0016829 - lyase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1410082

PRP19
Pre-mRNA-processing factor 19

4

1

Small-scale

0.694

High

251030

PRP17
Pre-mRNA-processing factor 17

3

2

High-throughput

0.667

High

1180482

C19L2
CWF19-like protein 2

3

1

High-throughput

0.667

High

1410073

CRNL1
Crooked neck-like protein 1

3

1

High-throughput

0.667

High

1410076

SYF1
Pre-mRNA-splicing factor SYF1

3

1

High-throughput

0.667

High

222521

PLRG1
Pleiotropic regulator 1

4

0

Small-scale

0.664

High

1404344

CDC5L
Cell division cycle 5-like protein

4

0

Small-scale

0.664

High

245146

AQR
RNA helicase aquarius

3

0

High-throughput

0.638

High

298065

SPF27
Pre-mRNA-splicing factor SPF27

3

0

High-throughput

0.638

High

1111227

SNW1
SNW domain-containing protein 1

3

0

High-throughput

0.638

High

1356562

CCD12
Coiled-coil domain-containing protein 12

3

0

High-throughput

0.638

High

1410070

GPTC1
G patch domain-containing protein 1

3

0

High-throughput

0.638

High

1410074

DHX35
Probable ATP-dependent RNA helicase DHX35

3

0

High-throughput

0.638

High

1410078

RBM22
Pre-mRNA-splicing factor RBM22

3

0

High-throughput

0.638

High

1410081

ISY1
Pre-mRNA-splicing factor ISY1 homolog

3

0

High-throughput

0.638

High

1410083

PPIE
Peptidyl-prolyl cis-trans isomerase E

3

0

High-throughput

0.638

High

1410071

WDR83
WD repeat domain-containing protein 83

3

2

High-throughput

0.609

High

351348

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.585

High

833555

BUD31
Protein BUD31 homolog

2

0

High-throughput

0.585

High

1201275

EAPP
E2F-associated phosphoprotein

2

0

High-throughput

0.585

High

1387397

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.585

High

1410084

SKAP
Small kinetochore-associated protein

2

0

High-throughput

0.585

High

289674

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

0

High-throughput

0.513

High

391081

TRFL
Lactotransferrin

1

0

High-throughput

0.513

High

1271359

ASGL1
Isoaspartyl peptidase/L-asparaginase

1

0

High-throughput

0.513

High

1410072

AFG2B
ATPase family gene 2 protein homolog B

1

0

High-throughput

0.513

High

1410079

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

High-throughput

0.513

High

1229504

C19L1
CWF19-like protein 1

1

1

High-throughput

0.489

High

1351339

BPIB1
BPI fold-containing family B member 1

1

1

High-throughput

0.489

High

1410077

BPIA1
BPI fold-containing family A member 1

1

1

High-throughput

0.489

High

1106683

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.486

High

997972

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.458

High

1326533

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

1

High-throughput

0.437

High

1389834

SIM12
Small integral membrane protein 12

1

1

High-throughput

0.437

High

1396782

SNX27
Sorting nexin-27

1

1

High-throughput

0.437

High

379772

IGHA2
Immunoglobulin heavy constant alpha 2

1

1

High-throughput

0.407

High

86031

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

0

High-throughput

0.279

Low

366204

HPT
Haptoglobin

1

0

High-throughput

0.279

Low

378715

IGJ
Immunoglobulin J chain

1

0

High-throughput

0.279

Low

379039

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.279

Low

1157306

PROL4
Proline-rich protein 4

1

0

High-throughput

0.279

Low

1351306

DMXL2
DmX-like protein 2

1

0

High-throughput

0.279

Low

1387151

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.279

Low

1410075

MUC5B
Mucin-5B

1

0

High-throughput

0.279

Low

1410080

DMBT1
Scavenger receptor cysteine-rich domain-containing protein DMBT1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025