HitPredict

Interactor 1: Q7KJ69 (Q7KJ69)
GEO01805p1 (IP02725p) (SKP1-related B) (SKPB)
Gene: SkpB

Interactor 2: Q9VDE3 (Q9VDE3)
LD08669p (Slimb) (Supernumerary limbs, isoform A) (Supernumerary limbs, isoform C)
Gene: slmb

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	15575970
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 161 Dm			1 510
+	Dm
		218244 O77430_DROME (1-161): 1.33e-81: 239: 72.84		O44382_DROME (1-510): 3.9e-151: 443: 99.61
+	Dm
		285012 O77430_DROME (1-161): 1.33e-81: 239: 72.84		Q9VDE3_DROME (1-510): 4.65e-151: 443: 100.00
+	Ce
		105479 SKR1_CAEEL (4-160): 1.21e-79: 235: 60.25		SEL10_CAEEL (268-509): 3.52e-56: 198: 31.60
+	Sp
		953229 SKP1_SCHPO (1-161): 3.03e-75: 223: 53.37		POF1_SCHPO (276-508): 3.18e-59: 207: 27.54
+	Hs
		929125 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBW1A_HUMAN (322-510): 1e-49: 182: 30.69
+	Mm
		1112932 SKP1_MOUSE (1-161): 8.98e-84: 245: 67.49		FBW1A_MOUSE (322-510): 1.14e-48: 178: 31.22
+	Xl
		1174984 SKP1_XENLA (1-161): 1.52e-83: 244: 67.49		TRCB_XENLA (322-510): 5.55e-49: 178: 31.22
+	Mm
		1131317 SKP1_MOUSE (1-161): 8.98e-84: 245: 67.49		FBW1B_MOUSE (322-510): 1.87e-48: 176: 31.22
+	Hs
		929110 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBW1B_HUMAN (322-510): 2.18e-48: 176: 30.69
+	Mm
		1257397 SKP1_MOUSE (1-161): 8.98e-84: 245: 67.49		FBXW7_MOUSE (358-510): 1.04e-37: 149: 28.57
+	Hs
		929021 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBXW7_HUMAN (358-510): 1.82e-37: 148: 28.57
+	Dm
		285042 O77430_DROME (1-161): 1.33e-81: 239: 72.84		FBXW7_DROME (358-510): 1.47e-38: 152: 28.57
+	Sp
		1000009 SKP1_SCHPO (1-161): 3.03e-75: 223: 53.37		POF11_SCHPO (45-320): 1.47e-39: 151: 20.43
+	Sp
		144900 SKP1_SCHPO (1-161): 3.03e-75: 223: 53.37		POP2_SCHPO (336-510): 8.21e-35: 140: 24.26
+	Hs
		928946 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBW10_HUMAN (337-490): 1.1e-27: 119: 23.00
+	Hs
		929116 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		FBXW2_HUMAN (366-502): 1.75e-24: 107: 27.34
+	Mm
		1351515 SKP1_MOUSE (1-161): 8.98e-84: 245: 67.49		Q9QUH1_MOUSE (366-502): 4.15e-23: 103: 26.62
+	Hs
		928956 SKP1_HUMAN (1-161): 1.52e-83: 244: 67.49		TRAF7_HUMAN (203-315): 9.52e-22: 100: 29.06
+	Sp
		953235 SKP1_SCHPO (1-161): 3.03e-75: 223: 53.37		POP1_SCHPO (416-509): 1.42e-13: 75.3: 19.15
+	Sc
		431143 SKP1_YEAST (4-161): 1.98e-66: 202: 38.95		CDC4_YEAST (408-509): 6.11e-20: 95.3: 25.00