Protein: MPK4
Mitogen-activated protein kinase 4 (AtMPK4) (MAP kinase 4) (EC 2.7.11.24)

Gene: MPK4
Organism: Arabidopsis thaliana
Interactions: 168
UniProt ID: Q39024

Gene Ontology (top 5):
GO:0000911 - cytokinesis by cell plate formation
GO:0004672 - protein kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1183708

M2K1
Mitogen-activated protein kinase kinase 1

8

20

Small-scale

0.972

High

1183764

M2K2
Mitogen-activated protein kinase kinase 2

6

20

Small-scale

0.957

High

1183730

M2K6
Mitogen-activated protein kinase kinase 6

5

20

Small-scale

0.929

High

306586

P2C25
Probable protein phosphatase 2C 25

4

12

Small-scale

0.909

High

1183666

MPK4
Mitogen-activated protein kinase 4

3

17

Small-scale

0.834

High

307346

MP3K2
Mitogen-activated protein kinase kinase kinase 9

1

10

Small-scale

0.777

High

1183308

MPK1
Mitogen-activated protein kinase 1

2

15

Small-scale

0.767

High

1182891

M3K1
Mitogen-activated protein kinase kinase kinase 1

2

17

Small-scale

0.754

High

1183783

P2C30
Probable protein phosphatase 2C 30

1

11

Small-scale

0.665

High

1183688

MKS1
Protein MKS1

3

0

Small-scale

0.658

High

75188

B3H4R6
Protein kinase superfamily protein

1

19

High-throughput

0.647

High

102091

PBL23
Probable serine/threonine-protein kinase PBL23

1

12

High-throughput

0.647

High

305982

M2K4
Mitogen-activated protein kinase kinase 4

1

20

High-throughput

0.647

High

515578

CALM3
Calmodulin-3

1

7

High-throughput

0.647

High

1081942

Q0WN54
Molecular chaperone Hsp40/DnaJ family protein

1

6

High-throughput

0.647

High

1182908

KSG6
Shaggy-related protein kinase zeta

1

18

High-throughput

0.647

High

1183670

CDPK3
Calcium-dependent protein kinase 3

1

12

High-throughput

0.647

High

1183679

TF3A
Transcription factor IIIA

1

6

High-throughput

0.647

High

1183689

CKL6
Casein kinase 1-like protein 6

1

9

High-throughput

0.647

High

1183704

CRCK2
Calmodulin-binding receptor-like cytoplasmic kinase 2

1

20

High-throughput

0.647

High

1183706

GRIK1
Serine/threonine-protein kinase GRIK1

1

16

High-throughput

0.647

High

1183767

WNK5
Probable serine/threonine-protein kinase WNK5

1

20

High-throughput

0.647

High

1183778

CDPKU
Calcium-dependent protein kinase 30

1

12

High-throughput

0.647

High

1167588

UBQ3
Polyubiquitin 3 [Cleaved into: Ubiquitin]

1

4

High-throughput

0.618

High

3950

A0A178UJ48
tRNA

2

1

High-throughput

0.584

High

60908

A2RVK1
At2g40290

1

6

High-throughput

0.579

High

1183687

Q8L7R1
At1g56300

1

8

High-throughput

0.579

High

1183715

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

9

High-throughput

0.579

High

1183742

CML11
Calmodulin-like protein 11

1

6

High-throughput

0.579

High

1183703

ASR3
Trihelix transcription factor ASR3

1

4

Small-scale

0.578

High

1183675

Q84JD1
START

2

5

High-throughput

0.566

High

199419

WRK25
Probable WRKY transcription factor 25

1

19

Small-scale

0.536

High

1183697

WRK33
Probable WRKY transcription factor 33

1

14

Small-scale

0.515

High

49252

ABI4
Ethylene-responsive transcription factor ABI4

1

20

High-throughput

0.501

High

90464

BBX19
B-box zinc finger protein 19

1

9

High-throughput

0.501

High

90510

BZP44
bZIP transcription factor 44

1

13

High-throughput

0.501

High

100418

TRB4
Telomere repeat-binding factor 4

1

5

High-throughput

0.501

High

101170

MYB88
Transcription factor MYB88

1

20

High-throughput

0.501

High

102848

MYB87
Transcription factor MYB87

1

20

High-throughput

0.501

High

103447

RVE2
Protein REVEILLE 2

1

20

High-throughput

0.501

High

103679

F4K9L7
Basic leucine-zipper 75

1

12

High-throughput

0.501

High

146603

WRK21
Probable WRKY transcription factor 21

1

20

High-throughput

0.501

High

235550

NAC29
NAC transcription factor 29

1

7

High-throughput

0.501

High

265661

NDK2
Nucleoside diphosphate kinase II, chloroplastic

1

6

High-throughput

0.501

High

607862

EFTU
Elongation factor Tu, chloroplastic

1

9

High-throughput

0.501

High

711978

AGL1
Agamous-like MADS-box protein AGL1

1

8

High-throughput

0.501

High

774879

AP3
Floral homeotic protein APETALA 3

1

5

High-throughput

0.501

High

841526

DR111
DNA-damage-repair/toleration protein 111

1

4

High-throughput

0.501

High

842078

RAP23
Ethylene-responsive transcription factor RAP2-3

1

20

High-throughput

0.501

High

884809

NC2B
Protein Dr1 homolog

1

15

High-throughput

0.501

High

1020089

CDC5L
Cell division cycle 5-like protein

1

20

High-throughput

0.501

High

1020263

CCA1
Protein CCA1

1

20

High-throughput

0.501

High

1020475

ARFE
Auxin response factor 5

1

14

High-throughput

0.501

High

1169101

MY115
Transcription factor MYB115

1

20

High-throughput

0.501

High

1182213

AGL15
Agamous-like MADS-box protein AGL15

1

17

High-throughput

0.501

High

1183667

Q39028
ATMYB2

1

20

High-throughput

0.501

High

1183668

TGA1
Transcription factor TGA1

1

7

High-throughput

0.501

High

1183669

SKP1A
SKP1-like protein 1A

1

6

High-throughput

0.501

High

1183671

ERF86
Ethylene-responsive transcription factor ERF086

1

20

High-throughput

0.501

High

1183672

RA211
Ethylene-responsive transcription factor RAP2-11

1

20

High-throughput

0.501

High

1183673

MYB56
Transcription factor MYB56

1

20

High-throughput

0.501

High

1183674

AGL53
Agamous-like MADS-box protein AGL53

1

20

High-throughput

0.501

High

1183677

DOF18
Dof zinc finger protein DOF1.8

1

20

High-throughput

0.501

High

1183682

MYB39
Transcription factor MYB39

1

20

High-throughput

0.501

High

1183683

GAT24
GATA transcription factor 24

1

8

High-throughput

0.501

High

1183684

Q8GYE4
Myb-like HTH transcriptional regulator family protein

1

20

High-throughput

0.501

High

1183685

NFYC9
Nuclear transcription factor Y subunit C-9

1

14

High-throughput

0.501

High

1183686

TRP1
Telomere repeat-binding protein 1

1

10

High-throughput

0.501

High

1183690

TCP4
Transcription factor TCP4

1

7

High-throughput

0.501

High

1183693

Q8RXU8
MYB transcription factor

1

11

High-throughput

0.501

High

1183694

AI5L1
ABSCISIC ACID-INSENSITIVE 5-like protein 1

1

8

High-throughput

0.501

High

1183696

BLH5
BEL1-like homeodomain protein 5

1

3

High-throughput

0.501

High

1183698

Q8VWG0
AtbZIP transcription factor

1

13

High-throughput

0.501

High

1183699

NFYA4
Nuclear transcription factor Y subunit A-4

1

8

High-throughput

0.501

High

1183701

PHLC
Myb family transcription factor PHL12

1

20

High-throughput

0.501

High

1183702

CLPB4
Chaperone protein ClpB4, mitochondrial

1

4

High-throughput

0.501

High

1183707

WRK69
Probable WRKY transcription factor 69

1

20

High-throughput

0.501

High

1183709

PFKA3
ATP-dependent 6-phosphofructokinase 3

1

10

High-throughput

0.501

High

1183710

HSFA5
Heat stress transcription factor A-5

1

8

High-throughput

0.501

High

1183711

LRP1
Protein LATERAL ROOT PRIMORDIUM 1

1

5

High-throughput

0.501

High

1183713

ARFB
Auxin response factor 2

1

14

High-throughput

0.501

High

1183716

MTK
Methylthioribose kinase

1

3

High-throughput

0.501

High

1183717

TCP22
Transcription factor TCP22

1

20

High-throughput

0.501

High

1183718

MYB20
Transcription factor MYB20

1

20

High-throughput

0.501

High

1183719

BH080
Transcription factor bHLH80

1

14

High-throughput

0.501

High

1183720

RGL1
DELLA protein RGL1

1

20

High-throughput

0.501

High

1183721

Q9C9D4
At1g72350

1

17

High-throughput

0.501

High

1183722

ERF21
Ethylene-responsive transcription factor ERF021

1

20

High-throughput

0.501

High

1183724

SCL28
Scarecrow-like protein 28

1

20

High-throughput

0.501

High

1183725

SM3L1
Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1

1

1

High-throughput

0.501

High

1183726

ALFL1
PHD finger protein ALFIN-LIKE 1

1

7

High-throughput

0.501

High

1183728

AGL80
Agamous-like MADS-box protein AGL80

1

10

High-throughput

0.501

High

1183729

Q9FJS9
At5g56840

1

20

High-throughput

0.501

High

1183731

Q9FL19
AGAMOUS-like 76

1

20

High-throughput

0.501

High

1183732

AGL75
Agamous-like MADS-box protein AGL75

1

20

High-throughput

0.501

High

1183733

GDL88
GDSL esterase/lipase At5g62930

1

3

High-throughput

0.501

High

1183734

NFYC4
Nuclear transcription factor Y subunit C-4

1

14

High-throughput

0.501

High

1183735

MY113
Transcription factor MYB113

1

20

High-throughput

0.501

High

1183736

DPA
Transcription factor-like protein DPA

1

2

High-throughput

0.501

High

1183737

TLP10
Tubby-like F-box protein 10

1

4

High-throughput

0.501

High

1183738

TCP21
Transcription factor TCP21

1

15

High-throughput

0.501

High

1183740

MY108
Transcription factor MYB108

1

20

High-throughput

0.501

High

1183741

P2A13
F-box protein PP2-A13

1

4

High-throughput

0.501

High

1183745

ETC1
MYB-like transcription factor ETC1

1

20

High-throughput

0.501

High

1183746

SCL3
Scarecrow-like protein 3

1

20

High-throughput

0.501

High

1183747

BZIP4
Basic leucine zipper 4

1

11

High-throughput

0.501

High

1183749

TOE2
AP2-like ethylene-responsive transcription factor TOE2

1

20

High-throughput

0.501

High

1183750

HEC3
Transcription factor HEC3

1

20

High-throughput

0.501

High

1183751

MYB41
Transcription factor MYB41

1

20

High-throughput

0.501

High

1183752

LAF1
Transcription factor LAF1

1

20

High-throughput

0.501

High

1183753

DRE1A
Dehydration-responsive element-binding protein 1A

1

20

High-throughput

0.501

High

1183754

Q9M0P7
Duplicated homeodomain-like superfamily protein

1

20

High-throughput

0.501

High

1183755

Q9M118
Myb domain protein 55

1

20

High-throughput

0.501

High

1183756

DOF32
Dof zinc finger protein DOF3.2

1

20

High-throughput

0.501

High

1183757

BZP61
Basic leucine zipper 61

1

13

High-throughput

0.501

High

1183758

SRS6
Protein SHI RELATED SEQUENCE 6

1

5

High-throughput

0.501

High

1183759

MUTE
Transcription factor MUTE

1

10

High-throughput

0.501

High

1183760

SCL21
Scarecrow-like protein 21

1

20

High-throughput

0.501

High

1183761

ERF18
Ethylene-responsive transcription factor ERF018

1

20

High-throughput

0.501

High

1183762

FLC
MADS-box protein FLOWERING LOCUS C

1

10

High-throughput

0.501

High

1183765

WRK40
Probable WRKY transcription factor 40

1

20

High-throughput

0.501

High

1183766

MYB92
Transcription factor MYB92

1

20

High-throughput

0.501

High

1183768

WER
Transcription factor WER

1

20

High-throughput

0.501

High

1183769

TAD2A
Transcriptional adapter ADA2a

1

4

High-throughput

0.501

High

1183771

SCRK1
Probable fructokinase-1

1

8

High-throughput

0.501

High

1183773

Q9SLH1
Myb domain protein 81

1

20

High-throughput

0.501

High

1183774

Q9SRB0
MYB transcription factor

1

20

High-throughput

0.501

High

1183777

MYB57
Transcription factor MYB57

1

20

High-throughput

0.501

High

1183779

SCL26
Scarecrow-like protein 26

1

20

High-throughput

0.501

High

1183780

ITPK3
Inositol-tetrakisphosphate 1-kinase 3

1

3

High-throughput

0.501

High

1183781

WRK53
Probable WRKY transcription factor 53

1

20

High-throughput

0.501

High

1183784

Q9XIE7
AGAMOUS-like 50

1

11

High-throughput

0.501

High

1183785

LHW
Transcription factor LHW

1

14

High-throughput

0.501

High

1183786

AHP1
Histidine-containing phosphotransfer protein 1

1

5

High-throughput

0.501

High

1183787

GAT20
GATA transcription factor 20

1

15

High-throughput

0.501

High

1183678

Q84K50
tRNA

1

1

High-throughput

0.481

High

200132

IF4E1
Eukaryotic translation initiation factor 4E-1

1

0

High-throughput

0.480

High

1183695

BZR1
Protein BRASSINAZOLE-RESISTANT 1

1

1

Small-scale

0.479

High

70581

A8MQF2
Alpha/beta-Hydrolases superfamily protein

1

6

High-throughput

0.457

High

198409

O22159
Expressed protein

1

2

High-throughput

0.457

High

198681

O22248
Alpha/beta-Hydrolases superfamily protein

1

2

High-throughput

0.457

High

307287

LBD31
LOB domain-containing protein 31

1

20

High-throughput

0.457

High

1183676

SINA3
E3 ubiquitin-protein ligase SINAT3

1

7

High-throughput

0.457

High

1183680

NFYB6
Nuclear transcription factor Y subunit B-6

1

15

High-throughput

0.457

High

1183681

Q8GUJ6
At4g28530

1

15

High-throughput

0.457

High

1183691

Q8RWE1
Metallo-beta-lactamase family protein

1

6

High-throughput

0.457

High

1183692

Q8RWR9
Uncharacterized protein At5g42070

1

3

High-throughput

0.457

High

1183700

MSRB7
Peptide methionine sulfoxide reductase B7

1

5

High-throughput

0.457

High

1183705

Q8VZP7
Mitochondrial substrate carrier family protein

1

13

High-throughput

0.457

High

1183723

PUB7
U-box domain-containing protein 7

1

8

High-throughput

0.457

High

1183727

NFYB2
Nuclear transcription factor Y subunit B-2

1

15

High-throughput

0.457

High

1183739

P24D4
Transmembrane emp24 domain-containing protein p24delta4

1

2

High-throughput

0.457

High

1183743

C05AK
Cytochrome P450 705A22

1

9

High-throughput

0.457

High

1183744

Q9LJY8
AT3g20100/MAL21_14

1

9

High-throughput

0.457

High

1183763

EAP3
Protein ENDOPLASMIC RETICULUM-ARRESTED PEN3

1

3

High-throughput

0.457

High

1183770

NFYB9
Nuclear transcription factor Y subunit B-9

1

15

High-throughput

0.457

High

1183772

CLC1
Clathrin light chain 1

1

2

High-throughput

0.457

High

1183775

TBL32
Protein trichome birefringence-like 32

1

3

High-throughput

0.457

High

1183776

LBD21
LOB domain-containing protein 21

1

20

High-throughput

0.457

High

1183782

LBD39
LOB domain-containing protein 39

1

20

High-throughput

0.457

High

1183788

Q9ZQN7
Homeodomain-like superfamily protein

1

4

High-throughput

0.457

High

1183789

PES1
Phytyl ester synthase 1, chloroplastic

1

2

High-throughput

0.457

High

101682

F4J7K1
Target of rapamycin complex subunit LST8

1

3

High-throughput

0.437

High

1183748

LST81
Target of rapamycin complex subunit LST8-1

1

4

High-throughput

0.407

High

90482

C0SVN2
TRF-like 10

1

0

High-throughput

0.261

Low

1183712

SKIP5
F-box protein SKIP5

1

0

High-throughput

0.261

Low

1183714

Q9C5C1
Uncharacterized protein At4g31330

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025