HitPredict

Interactor 1: TAD2A (Q7KSD8)
Transcriptional adapter 2A (dADA2a)
Gene: Ada2a

Interactor 2: Q9VTZ1 (Q9VTZ1)
Histone acetyltransferase GCN5 (EC 2.3.1.48)
Gene: Gcn5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.958

Property	Details
Experiments	16428443, 12697829, 12482983, 18327268, 20813260, 17030603, 22345504
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0140672 - ATAC complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 562 Dm			1 813
+	Dm
		283712 TAD2A_DROME (1-562): 0: 668: 100.00		O76216_DROME (1-813): 0: 1138: 99.63
+	Mm
		1208540 TAD2A_MOUSE (81-557): 5.28e-143: 422: 31.41		KAT2B_MOUSE (35-813): 0: 1069: 44.82
+	Hs
		266399 TAD2A_HUMAN (81-557): 7.67e-146: 429: 30.99		KAT2B_HUMAN (71-813): 0: 1026: 47.27
+	Dm
		1212009 TAD2B_DROME (92-441): 2.83e-96: 305: 24.52		Q9VTZ1_DROME (1-813): 0: 1141: 100.00
+	Hs
		266398 TAD2A_HUMAN (81-557): 7.67e-146: 429: 30.99		KAT2A_HUMAN (58-813): 0: 1014: 47.23
+	Dm
		283714 TAD2B_DROME (92-441): 2.83e-96: 305: 24.52		O76216_DROME (1-813): 0: 1138: 99.63
+	Mm
		1208541 TAD2A_MOUSE (81-557): 5.28e-143: 422: 31.41		KAT2A_MOUSE (61-813): 0: 1020: 47.40
+	Hs
		1198566 TAD2B_HUMAN (89-560): 1.21e-136: 405: 23.57		KAT2B_HUMAN (71-813): 0: 1026: 47.27
+	Hs
		1198565 TAD2B_HUMAN (89-560): 1.21e-136: 405: 23.57		KAT2A_HUMAN (58-813): 0: 1014: 47.23
+	Sc
		970392 ADA2_YEAST (91-555): 1.56e-137: 407: 21.78		GCN5_YEAST (398-811): 1.24e-165: 488: 37.68
+	At
		1308015 TAD2A_ARATH (91-553): 1.63e-127: 386: 20.23		GCN5_ARATH (453-806): 3.2e-149: 451: 42.03
+	At
		1308007 TAD2B_ARATH (73-553): 4.59e-128: 385: 21.77		GCN5_ARATH (453-806): 3.2e-149: 451: 42.03
+	Sc
		797934 RSC8_YEAST (42-343): 5.86e-52: 188: 12.95		GCN5_YEAST (398-811): 1.24e-165: 488: 37.68
+	Pf
		1211774 Q8I5G5_PLAF7 (58-209): 8.72e-29: 123: 13.77		Q8IB67_PLAF7 (435-808): 1.35e-136: 442: 38.68
+	At
		1275616 SWI3C_ARATH (74-437): 7.72e-44: 168: 12.73		GTE11_ARATH (623-810): 2.98e-39: 156: 21.33
+	Sc
		728711 RSC8_YEAST (42-343): 5.86e-52: 188: 12.95		BDF1_YEAST (640-812): 2.1e-22: 104: 20.57
+	At
		1195144 SWI3B_ARATH (76-411): 4.25e-30: 125: 12.36		GTE11_ARATH (623-810): 2.98e-39: 156: 21.33
+	At
		1258938 SWI3A_ARATH (95-387): 2.17e-12: 71.5: 13.77		GTE11_ARATH (623-810): 2.98e-39: 156: 21.33