HitPredict

Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: DAB2P (Q5VWQ8)
Disabled homolog 2-interacting protein (DAB2 interaction protein) (DAB2-interacting protein) (ASK-interacting protein 1) (AIP-1) (DOC-2/DAB-2 interactive protein)
Gene: DAB2IP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

The method score is based on:

Property	Details
Experiments	17389591, 15310755, 24912918
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030163 - protein catabolic process GO:0031435 - mitogen-activated protein kinase kinase kinase binding and 7 others more... GO:0035591 - signaling adaptor activity GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0043254 - regulation of protein-containing complex assembly GO:0043507 - positive regulation of JUN kinase activity GO:0044877 - protein-containing complex binding GO:0045087 - innate immune response GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	501
Hs

1	1189

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024