HitPredict

Interactor 1: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Interactor 2: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 20360068, 16472737
Identification Methods affinity chromatography technology, x-ray crystallography, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KA1~Pkinase, KA1~UBA, Pkinase~Pkinase, Pkinase~UBA, UBA~UBA
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0000287 - magnesium ion binding
GO:0000422 - autophagy of mitochondrion
GO:0001764 - neuron migration
GO:0003723 - RNA binding
and 34 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 788
Hs

1 788
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024