Protein: WDR33
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)

Gene: WDR33
Organism: Homo sapiens
Interactions: 140
UniProt ID: Q9C0J8

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005581 - collagen trimer
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

340774

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

5

4

Small-scale

0.919

High

66975

CPS4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein

3

4

High-throughput

0.861

High

1083434

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

4

18

Small-scale

0.860

High

1111253

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.691

High

1248075

FIP1
Pre-mRNA 3'-end-processing factor FIP1

4

2

Small-scale

0.683

High

1368752

SYMPK
Symplekin

4

1

Small-scale

0.683

High

889659

CLK2
Dual specificity protein kinase CLK2

3

13

High-throughput

0.675

High

1111861

TRA2A
Transformer-2 protein homolog alpha

3

5

High-throughput

0.667

High

1290707

ZCH18
Zinc finger CCCH domain-containing protein 18

3

15

High-throughput

0.667

High

191394

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

3

5

High-throughput

0.662

High

1421326

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

3

10

Small-scale

0.662

High

1145357

RNPS1
RNA-binding protein with serine-rich domain 1

3

8

High-throughput

0.657

High

1421323

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

3

10

Small-scale

0.650

High

447411

NPM
Nucleophosmin

3

5

High-throughput

0.640

High

1239661

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

4

High-throughput

0.628

High

175198

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.618

High

1007262

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

754977

H2B1B
Histone H2B type 1-B

1

10

High-throughput

0.618

High

971049

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

11

High-throughput

0.618

High

980286

H4
Histone H4

1

8

High-throughput

0.618

High

1128109

DHX8
ATP-dependent RNA helicase DHX8

1

8

High-throughput

0.618

High

1311850

DHX40
Probable ATP-dependent RNA helicase DHX40

1

8

High-throughput

0.618

High

1421313

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

12

High-throughput

0.618

High

414573

P53
Cellular tumor antigen p53

2

6

High-throughput

0.614

High

473062

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

9

High-throughput

0.611

High

1421322

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.608

High

242852

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

485398

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

14

Small-scale

0.584

High

589628

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

696441

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

High-throughput

0.584

High

769115

RFA3
Replication protein A 14 kDa subunit

2

2

High-throughput

0.584

High

399623

VTNC
Vitronectin

2

5

High-throughput

0.574

High

1278565

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

5

High-throughput

0.574

High

1411286

LZTS2
Leucine zipper putative tumor suppressor 2

2

20

High-throughput

0.574

High

1092488

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

9

High-throughput

0.553

High

1227416

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.553

High

1421314

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

549232

CDK4
Cyclin-dependent kinase 4

1

9

Small-scale

0.550

High

332041

KAT7
Histone acetyltransferase KAT7

1

4

High-throughput

0.541

High

688142

EF1G
Elongation factor 1-gamma

1

4

High-throughput

0.541

High

1407865

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.541

High

1415347

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

3

High-throughput

0.541

High

1421327

ZHX1
Zinc fingers and homeoboxes protein 1

1

5

High-throughput

0.541

High

134861

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.536

High

230104

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

2

High-throughput

0.536

High

478201

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

High-throughput

0.536

High

542206

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

682601

S100P
Protein S100-P

1

2

High-throughput

0.536

High

775304

FUS
RNA-binding protein FUS

1

9

High-throughput

0.536

High

879753

MAPK2
MAP kinase-activated protein kinase 2

1

1

High-throughput

0.536

High

1025422

CDK6
Cyclin-dependent kinase 6

1

8

High-throughput

0.536

High

1099523

SRSF6
Serine/arginine-rich splicing factor 6

1

17

High-throughput

0.536

High

1148785

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

4

High-throughput

0.536

High

1160073

SRSF7
Serine/arginine-rich splicing factor 7

1

15

High-throughput

0.536

High

1160285

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

9

High-throughput

0.536

High

1358660

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

7

High-throughput

0.536

High

1387266

HDA11
Histone deacetylase 11

1

18

High-throughput

0.536

High

1399729

RBM14
RNA-binding protein 14

1

9

High-throughput

0.536

High

1404374

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.536

High

1421318

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.536

High

1421319

DYRK4
Dual specificity tyrosine-phosphorylation-regulated kinase 4

1

12

High-throughput

0.536

High

1051417

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

1209160

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

933266

AIF1
Allograft inflammatory factor 1

1

0

High-throughput

0.513

High

508581

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.501

High

1408413

SH3G3
Endophilin-A3

1

2

High-throughput

0.494

High

1421333

GIT1
ARF GTPase-activating protein GIT1

1

10

High-throughput

0.494

High

457126

CAN1
Calpain-1 catalytic subunit

1

3

High-throughput

0.489

High

567073

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

5

High-throughput

0.489

High

1384125

ARRD3
Arrestin domain-containing protein 3

1

6

High-throughput

0.489

High

1393312

SAHH3
Adenosylhomocysteinase 3

1

2

High-throughput

0.489

High

1421330

WASF3
Actin-binding protein WASF3

1

4

High-throughput

0.489

High

1421331

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.489

High

129403

MEN1
Menin

1

3

High-throughput

0.479

High

130606

SPT5H
Transcription elongation factor SPT5

1

7

High-throughput

0.479

High

132284

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.479

High

260424

BRD4
Bromodomain-containing protein 4

1

19

High-throughput

0.479

High

320042

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

331303

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

341672

EYA4
Protein phosphatase EYA4

1

13

High-throughput

0.479

High

401450

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

425624

ISG15
Ubiquitin-like protein ISG15

1

10

High-throughput

0.479

High

520356

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

607084

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

712271

TKT
Transketolase

1

4

High-throughput

0.479

High

750474

CSTF2
Cleavage stimulation factor subunit 2

1

5

High-throughput

0.479

High

765867

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.479

High

862431

YAP1
Transcriptional coactivator YAP1

1

8

High-throughput

0.479

High

891308

GSK3A
Glycogen synthase kinase-3 alpha

1

7

High-throughput

0.479

High

905117

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

986702

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

1005074

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1022833

RHG04
Rho GTPase-activating protein 4

1

3

High-throughput

0.479

High

1024824

VIGLN
Vigilin

1

14

High-throughput

0.479

High

1035897

KIF23
Kinesin-like protein KIF23

1

13

High-throughput

0.479

High

1100352

TIF1B
Transcription intermediary factor 1-beta

1

11

High-throughput

0.479

High

1129735

MDC1
Mediator of DNA damage checkpoint protein 1

1

16

High-throughput

0.479

High

1140817

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1146811

PCBP1
Poly(rC)-binding protein 1

1

10

High-throughput

0.479

High

1152626

ELAV1
ELAV-like protein 1

1

3

High-throughput

0.479

High

1235514

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

1257125

PAXI1
PAX-interacting protein 1

1

14

High-throughput

0.479

High

1276757

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1289299

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

1313412

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1339698

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1351151

SP7
Transcription factor Sp7

1

13

High-throughput

0.479

High

1367212

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1369834

CELF1
CUGBP Elav-like family member 1

1

5

High-throughput

0.479

High

1406770

BARD1
BRCA1-associated RING domain protein 1

1

6

High-throughput

0.479

High

1421311

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

1421315

ECT2
Protein ECT2

1

16

High-throughput

0.479

High

1421320

RNC
Ribonuclease 3

1

3

High-throughput

0.479

High

1421321

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1421324

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

1421325

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1421329

MYO6
Unconventional myosin-VI

1

8

High-throughput

0.479

High

895466

SPB8
Serpin B8

1

8

High-throughput

0.470

High

1339168

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1409550

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

135340

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

15

High-throughput

0.445

High

480302

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.445

High

991420

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.445

High

1016604

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.445

High

1203256

ODFP2
Outer dense fiber protein 2

1

14

High-throughput

0.445

High

1421312

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

5

High-throughput

0.445

High

1421316

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.445

High

1421332

YBOX2
Y-box-binding protein 2

1

4

High-throughput

0.445

High

1241952

FBX42
F-box only protein 42

1

5

High-throughput

0.437

High

1257040

SYDE1
Rho GTPase-activating protein SYDE1

1

6

High-throughput

0.437

High

1421317

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

6

High-throughput

0.437

High

1421328

AGO1
Protein argonaute-1

1

0

High-throughput

0.426

High

1180865

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

1

High-throughput

0.407

High

1226261

CP135
Centrosomal protein of 135 kDa

1

13

High-throughput

0.407

High

1396576

C170L
Cep170-like protein

1

2

High-throughput

0.407

High

762491

PROF2
Profilin-2

1

0

High-throughput

0.282

High

515903

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

1092815

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1241343

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.249

Low

1332891

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025