HitPredict

Interactor 1: RRAGA (Q7L523)
Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1)
Gene: RRAGA

Interactor 2: S38A9 (Q8NBW4)
Neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11)
Gene: SLC38A9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	25567906, 26186194, 28514442, 33961781, 25561175, 32433612
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0032008 - positive regulation of TOR signaling GO:0071230 - cellular response to amino acid stimulus GO:1904263 - positive regulation of TORC1 signaling and 1 others more... GO:1990877 - FNIP-folliculin RagC/D GAP
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 561
+	Hs
		1139771 RRAGB_HUMAN (1-313): 1.71e-169: 476: 90.03		S38A9_HUMAN (1-561): 0: 1067: 100.00
+	Mm
		1194443 RRAGA_MOUSE (1-313): 7.68e-174: 485: 100.00		S38A9_MOUSE (1-561): 0: 1002: 91.27
+	Hs
		1240548 RRAGC_HUMAN (5-235): 1.27e-100: 302: 25.42		S38A9_HUMAN (1-561): 0: 1067: 100.00
+	Hs
		1240549 RRAGD_HUMAN (3-235): 4.97e-100: 301: 24.79		S38A9_HUMAN (1-561): 0: 1067: 100.00