Interactor 1: RRAGA (Q7L523)
Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1)
Gene: RRAGA

Interactor 2: RRAGC (Q9HB90)
Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929)
Gene: RRAGC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26186194, 16189514, 25936802, 28514442, 31601708, 33157014, 11073942, 33961781, 36608670, 26588989, 21816923, 23184942, 24337580, 20381137, 28716898, 21981924, 25567906, 25561175, 22424946
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gtr1_RagA~Gtr1_RagA
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 17 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 313
Hs

1 399
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Sp
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024