HitPredict

Interactor 1: RRAGA (Q7L523)
Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1)
Gene: RRAGA

Interactor 2: LTOR2 (Q9Y2Q5)
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)
Gene: LAMTOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	33961781, 20381137, 25567906, 22980980, 25561175
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0008104 - protein localization GO:0032008 - positive regulation of TOR signaling GO:0071230 - cellular response to amino acid stimulus GO:1904263 - positive regulation of TORC1 signaling and 1 others more... GO:1990877 - FNIP-folliculin RagC/D GAP
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 125
+	Hs
		1139783 RRAGB_HUMAN (1-313): 1.71e-169: 476: 90.03		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		1335161 RRAGC_HUMAN (5-235): 1.27e-100: 302: 25.42		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00
+	Hs
		1343500 RRAGD_HUMAN (3-235): 4.97e-100: 301: 24.79		LTOR2_HUMAN (1-125): 1.93e-61: 185: 100.00