Interactor 1: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Interactor 2: NCKP1 (Q9Y2A7)
Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: NCKAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 27173435, 33961781, 35271311, 35235311, 37071682, 21107423, 19363480, 15294869, 15296760
Identification Methods affinity chromatography technology, cross-linking study, pull down, molecular sieving, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FragX_IP~Nckap1
Common GO terms GO:0000902 - cell morphogenesis
GO:0001726 - ruffle
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0010592 - positive regulation of lamellipodium assembly
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1253
Hs

1 1128
+ Mm
+ Mm
+ Hs
+ Dm
+ Ce
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024