Interactor 1: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.798

The method score is based on:

Property Details
Experiments 35271311, 21107423
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FragX_IP~WH2
Common GO terms GO:0001726 - ruffle
GO:0005829 - cytosol
GO:0010592 - positive regulation of lamellipodium assembly
GO:0016601 - Rac protein signal transduction
GO:0030027 - lamellipodium
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1253
Hs

1 498
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Bt
+ Hs
+ Dm
+ Dd

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Last updated: 15 Jul 2024