Protein: PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)

Gene: PIGU
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9H490

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1268719

GPI8
GPI-anchor transamidase

4

1

Small-scale

0.691

High

310349

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

1298940

NECT4
Nectin-4

3

0

High-throughput

0.638

High

1253894

SPP2B
Signal peptide peptidase-like 2B

2

3

High-throughput

0.628

High

1330614

CLC5A
C-type lectin domain family 5 member A

2

2

High-throughput

0.611

High

315908

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

1281736

PIGT
GPI transamidase component PIG-T

2

0

High-throughput

0.602

High

1301690

PIGS
GPI transamidase component PIG-S

2

1

Small-scale

0.601

High

1268652

LPAR1
Lysophosphatidic acid receptor 1

2

0

High-throughput

0.585

High

390528

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

0

High-throughput

0.559

High

876194

PAR2
Proteinase-activated receptor 2

1

4

High-throughput

0.541

High

134411

ACKR2
Atypical chemokine receptor 2

1

1

High-throughput

0.536

High

156931

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

326215

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

626726

EDNRA
Endothelin-1 receptor

1

1

High-throughput

0.536

High

644694

NKG2C
NKG2-C type II integral membrane protein

1

2

High-throughput

0.536

High

686384

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.536

High

782473

P2RY2
P2Y purinoceptor 2

1

4

High-throughput

0.536

High

814308

GLR
Glucagon receptor

1

1

High-throughput

0.536

High

1031077

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.536

High

1202736

P2RY8
P2Y purinoceptor 8

1

4

High-throughput

0.536

High

1291481

TSN17
Tetraspanin-17

1

1

High-throughput

0.536

High

1330611

GPR35
G-protein coupled receptor 35

1

3

High-throughput

0.536

High

1330618

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.536

High

213161

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

245417

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

276392

AP1G2
AP-1 complex subunit gamma-like 2

1

0

High-throughput

0.513

High

310812

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.513

High

313960

PIGN
GPI ethanolamine phosphate transferase 1

1

0

High-throughput

0.513

High

380193

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.513

High

456191

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.513

High

646299

STOM
Stomatin

1

0

High-throughput

0.513

High

723912

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.513

High

877580

CAD13
Cadherin-13

1

0

High-throughput

0.513

High

1016676

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

1085222

PRSS8
Prostasin

1

0

High-throughput

0.513

High

1129726

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.513

High

1156893

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.513

High

1274316

NAR4
Ecto-ADP-ribosyltransferase 4

1

0

High-throughput

0.513

High

1283279

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1288910

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

1293432

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.513

High

1325971

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

1326943

ACH10
Neuronal acetylcholine receptor subunit alpha-10

1

0

High-throughput

0.513

High

1327040

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

1329461

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.513

High

1330612

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.513

High

1330622

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.513

High

348921

RASN
GTPase NRas

1

1

High-throughput

0.479

High

350548

RASK
GTPase KRas

1

1

High-throughput

0.479

High

377679

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

436505

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.479

High

545613

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

674880

AGTR1
Type-1 angiotensin II receptor

1

1

High-throughput

0.479

High

890418

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

900894

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

951335

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

1282642

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1328854

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.479

High

1330619

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.479

High

48505

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.458

High

205976

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

391176

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

599768

SCF
Kit ligand

1

0

High-throughput

0.458

High

616643

GLRA2
Glycine receptor subunit alpha-2

1

0

High-throughput

0.458

High

668980

PML
Protein PML

1

0

High-throughput

0.458

High

795279

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

839130

EMD
Emerin

1

0

High-throughput

0.458

High

845245

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

847656

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

970312

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

0

High-throughput

0.458

High

1053187

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1087610

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1185632

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.458

High

1230370

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.458

High

1303566

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1307602

G3ST1
Galactosylceramide sulfotransferase

1

0

High-throughput

0.458

High

1329277

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1330609

FNDC4
Fibronectin type III domain-containing protein 4

1

0

High-throughput

0.458

High

1330610

RN121
E3 ubiquitin ligase RNF121

1

0

Small-scale

0.458

High

1330620

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.458

High

1330621

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.458

High

1156712

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1269605

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1292864

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1330616

TSP50
Probable threonine protease PRSS50

1

1

High-throughput

0.437

High

529715

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1236088

KASH5
Protein KASH5

2

0

High-throughput

0.316

High

1021889

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

1330617

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

944936

RED1
Double-stranded RNA-specific editase 1

1

0

High-throughput

0.249

Low

1086784

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1171697

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1203849

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1204335

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1240298

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1294899

TXD15
Thioredoxin domain-containing protein 15

1

0

High-throughput

0.249

Low

1330613

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1330615

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024