HitPredict

Interactor 1: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Interactor 2: KLH42 (Q9P2K6)
Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5)
Gene: KLHL42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	19615732, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 505
+	Hs
		1121231 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH22_HUMAN (6-501): 8.93e-110: 341: 19.21
+	Hs
		1185018 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH20_HUMAN (4-499): 2.21e-108: 336: 18.99
+	Hs
		1185001 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH13_HUMAN (2-505): 5.44e-102: 321: 18.56
+	Hs
		1184999 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLHL9_HUMAN (2-504): 4.12e-102: 320: 17.34
+	Hs
		299521 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH18_HUMAN (2-498): 3.63e-100: 314: 17.40
+	Hs
		1184998 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLHL8_HUMAN (2-499): 1.05e-94: 301: 15.92
+	Hs
		1121474 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH26_HUMAN (4-504): 1.01e-88: 285: 19.30
+	Hs
		1164611 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH24_HUMAN (3-503): 6.17e-88: 283: 16.70
+	Hs
		1120774 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH12_HUMAN (56-450): 1.45e-54: 194: 13.03
+	Hs
		1184911 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH23_HUMAN (171-392): 6.43e-35: 139: 23.89
+	Hs
		1153783 CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00		KLH10_HUMAN (329-498): 3.32e-26: 114: 14.04