Interactor 1: DET1 (Q7L5Y6)
DET1 homolog (De-etiolated-1 homolog)
Gene: DET1

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.55 0.722

The method score is based on:

Property Details
Experiments 17452440, 28514442, 14739464, 30692133, 31155351, 33961781, 32041890, 33911083, 21572435, 25117710
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016567 - protein ubiquitination
GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 0

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Last updated: 15 Jul 2024