Protein: KLH13
Kelch-like protein 13 (BTB and kelch domain-containing protein 2)

Gene: KLH13, KLHL13
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q9P2N7

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0032465 - regulation of cytokinesis
GO:0051301 - cell division

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114525

CUL3
Cullin-3

13

20

Small-scale

0.980

High

1454622

KLHL9
Kelch-like protein 9

9

19

Small-scale

0.967

High

1199734

KLH22
Kelch-like protein 22

7

19

Small-scale

0.958

High

1452114

KLH28
Kelch-like protein 28

2

19

High-throughput

0.811

High

161310

ENC1
Ectoderm-neural cortex protein 1

2

19

High-throughput

0.776

High

1094434

CSN1
COP9 signalosome complex subunit 1

2

17

High-throughput

0.776

High

1397881

KLH15
Kelch-like protein 15

2

19

High-throughput

0.776

High

1454747

FXL17
F-box/LRR-repeat protein 17

2

13

High-throughput

0.776

High

1454749

KLH21
Kelch-like protein 21

2

19

Small-scale

0.737

High

1454580

KLH14
Kelch-like protein 14

1

20

High-throughput

0.691

High

322333

GLSK
Glutaminase kidney isoform, mitochondrial

1

4

High-throughput

0.665

High

1391823

AURKB
Aurora kinase B

2

6

Small-scale

0.650

High

508757

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.647

High

958728

CSN2
COP9 signalosome complex subunit 2

3

20

High-throughput

0.643

High

1200019

KLH26
Kelch-like protein 26

2

18

High-throughput

0.637

High

1272583

CSN6
COP9 signalosome complex subunit 6

2

12

High-throughput

0.628

High

1370428

CSN5
COP9 signalosome complex subunit 5

2

13

High-throughput

0.628

High

1403317

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

1

High-throughput

0.618

High

1406134

CSN8
COP9 signalosome complex subunit 8

2

3

High-throughput

0.601

High

1413211

CSN4
COP9 signalosome complex subunit 4

2

3

High-throughput

0.601

High

1454748

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

2

13

Small-scale

0.584

High

329115

KLHL2
Kelch-like protein 2

1

18

High-throughput

0.575

High

1112752

CUL1
Cullin-1

1

20

High-throughput

0.575

High

1199046

KLH12
Kelch-like protein 12

1

19

High-throughput

0.575

High

1247814

KLH24
Kelch-like protein 24

1

19

High-throughput

0.575

High

1430057

KLH25
Kelch-like protein 25

1

20

High-throughput

0.575

High

1454745

KLH13
Kelch-like protein 13

1

19

High-throughput

0.575

High

377319

VIP
VIP peptides [Cleaved into: Intestinal peptide PHV-42

2

1

High-throughput

0.549

High

943327

RBM11
Splicing regulator RBM11

2

2

High-throughput

0.549

High

1358034

TM171
Transmembrane protein 171

2

1

High-throughput

0.549

High

1454754

PCDG5
Protocadherin gamma-A5

2

9

High-throughput

0.549

High

167661

GIPC1
PDZ domain-containing protein GIPC1

1

2

High-throughput

0.536

High

320786

UBXN7
UBX domain-containing protein 7

1

6

High-throughput

0.536

High

762096

MPI
Mannose-6-phosphate isomerase

1

1

High-throughput

0.536

High

833031

ETV6
Transcription factor ETV6

1

4

High-throughput

0.536

High

907611

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

4

High-throughput

0.536

High

954634

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.536

High

1099801

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

1

High-throughput

0.536

High

1353344

PAR3L
Partitioning defective 3 homolog B

1

5

High-throughput

0.536

High

1367817

TFG
Protein TFG

1

3

High-throughput

0.536

High

1391968

DCNL1
DCN1-like protein 1

1

10

High-throughput

0.536

High

1398178

HEXI2
Protein HEXIM2

1

3

High-throughput

0.536

High

1446576

NXT2
NTF2-related export protein 2

1

1

High-throughput

0.536

High

1454746

CSN7A
COP9 signalosome complex subunit 7a

1

5

High-throughput

0.536

High

772526

IRS1
Insulin receptor substrate 1

1

6

Small-scale

0.515

High

378790

LV657
Immunoglobulin lambda variable 6-57

1

4

High-throughput

0.514

High

1453245

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

506040

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

2

2

High-throughput

0.504

High

906808

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

5

Small-scale

0.501

High

253912

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

325146

HEXI1
Protein HEXIM1

1

3

High-throughput

0.489

High

342683

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

345217

ZMYM6
Zinc finger MYM-type protein 6

1

1

High-throughput

0.489

High

651609

IBP4
Insulin-like growth factor-binding protein 4

1

4

High-throughput

0.489

High

652685

GNLY
Granulysin

1

1

High-throughput

0.489

High

1099642

NOGG
Noggin

1

1

High-throughput

0.489

High

1120979

TRI29
Tripartite motif-containing protein 29

1

6

High-throughput

0.489

High

1122367

SCRIB
Protein scribble homolog

1

4

High-throughput

0.489

High

1179781

TMM44
Transmembrane protein 44

1

1

High-throughput

0.489

High

1219760

ZMYM4
Zinc finger MYM-type protein 4

1

2

High-throughput

0.489

High

1220495

F219B
Protein FAM219B

1

3

High-throughput

0.489

High

1248531

KIRR2
Kin of IRRE-like protein 2

1

5

High-throughput

0.489

High

1308139

LUR1L
Leucine rich adaptor protein 1-like

1

1

High-throughput

0.489

High

1308605

NUDC3
NudC domain-containing protein 3

1

20

High-throughput

0.489

High

1322367

ZN444
Zinc finger protein 444

1

7

High-throughput

0.489

High

1336964

BHE23
Class E basic helix-loop-helix protein 23

1

3

High-throughput

0.489

High

1340973

MCFD2
Multiple coagulation factor deficiency protein 2

1

1

High-throughput

0.489

High

1347304

FIBIN
Fin bud initiation factor homolog

1

1

High-throughput

0.489

High

1356254

MZB1
Marginal zone B- and B1-cell-specific protein

1

3

High-throughput

0.489

High

1394356

ZN414
Zinc finger protein 414

1

2

High-throughput

0.489

High

1410800

SYT3
Synaptotagmin-3

1

2

High-throughput

0.489

High

1415248

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.489

High

1416838

C1QT3
Complement C1q tumor necrosis factor-related protein 3

1

7

High-throughput

0.489

High

1454755

CXA3
Gap junction alpha-3 protein

1

1

High-throughput

0.489

High

462000

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

468870

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

957536

UBC12
NEDD8-conjugating enzyme Ubc12

1

15

High-throughput

0.479

High

984002

RBX1
E3 ubiquitin-protein ligase RBX1

1

8

Small-scale

0.479

High

1333356

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1397514

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1435147

ES8L2
Epidermal growth factor receptor kinase substrate 8-like protein 2

1

1

High-throughput

0.479

High

1446985

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1454752

ARI1
E3 ubiquitin-protein ligase ARIH1

1

14

High-throughput

0.479

High

1448515

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

992362

SKP1
S-phase kinase-associated protein 1

1

2

High-throughput

0.445

High

1105184

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.445

High

1401896

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.445

High

1454751

CSN3
COP9 signalosome complex subunit 3

1

20

High-throughput

0.445

High

412737

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

769398

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

873125

SOX9
Transcription factor SOX-9

1

9

Small-scale

0.437

High

1169044

CSPP1
Centrosome and spindle pole-associated protein 1

1

1

High-throughput

0.437

High

1232039

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

1

High-throughput

0.437

High

1255909

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

64183

ARG35
Rho guanine nucleotide exchange factor 35

1

1

High-throughput

0.407

High

167467

WNT9A
Protein Wnt-9a

1

3

High-throughput

0.407

High

482271

PAEP
Glycodelin

1

2

High-throughput

0.407

High

484234

PGFRB
Platelet-derived growth factor receptor beta

1

5

High-throughput

0.407

High

1322548

MIER1
Mesoderm induction early response protein 1

1

2

High-throughput

0.407

High

1394688

KIRR1
Kin of IRRE-like protein 1

1

5

High-throughput

0.407

High

1395537

PGBD1
PiggyBac transposable element-derived protein 1

1

4

High-throughput

0.407

High

1454750

PCDGG
Protocadherin gamma-B4

1

9

High-throughput

0.407

High

1454753

PCDGH
Protocadherin gamma-B5

1

9

High-throughput

0.407

High

589922

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

1435053

CIAO3
Cytosolic iron-sulfur assembly component 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025