HitPredict

Interactor 1: DET1 (Q7L5Y6)
DET1 homolog (De-etiolated-1 homolog)
Gene: DET1

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 372
+	Hs
		1185066 DET1_HUMAN (1-550): 0: 854: 100.00		TRIB2_HUMAN (52-371): 1.1e-115: 341: 60.25
+	Hs
		1185080 DET1_HUMAN (1-550): 0: 854: 100.00		TRIB3_HUMAN (89-360): 1.98e-86: 267: 51.65
+	Hs
		1185061 DET1_HUMAN (1-550): 0: 854: 100.00		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31