Protein: CERS2
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)

Gene: CERS2
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q96G23

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0019216 - regulation of lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1291807

SG196
Protein O-mannose kinase

4

4

High-throughput

0.699

High

648062

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

3

1

Small-scale

0.672

High

623327

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

3

1

High-throughput

0.667

High

1168245

CERS6
Ceramide synthase 6

1

6

Small-scale

0.647

High

415448

ATPB
ATP synthase subunit beta, mitochondrial

2

3

High-throughput

0.628

High

173347

S22A1
Solute carrier family 22 member 1

2

2

Small-scale

0.619

High

1268624

LPAR1
Lysophosphatidic acid receptor 1

3

13

High-throughput

0.609

High

1291835

IR3IP
Immediate early response 3-interacting protein 1

2

1

High-throughput

0.606

High

1291819

ELOV5
Very long chain fatty acid elongase 5

2

8

Small-scale

0.584

High

1081242

NF2L2
Nuclear factor erythroid 2-related factor 2

1

2

Small-scale

0.582

High

303939

YIF1A
Protein YIF1A

2

0

High-throughput

0.580

High

432151

HS90A
Heat shock protein HSP 90-alpha

1

3

High-throughput

0.578

High

626753

NK1R
Substance-P receptor

2

5

High-throughput

0.574

High

658276

5HT2C
5-hydroxytryptamine receptor 2C

2

9

High-throughput

0.574

High

783712

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

8

High-throughput

0.574

High

1083477

C3AR
C3a anaphylatoxin chemotactic receptor

2

20

High-throughput

0.574

High

370194

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

426794

ASGR1
Asialoglycoprotein receptor 1

2

2

Small-scale

0.565

High

426858

ASGR2
Asialoglycoprotein receptor 2

2

4

Small-scale

0.565

High

1291796

B2L13
Bcl-2-like protein 13

1

1

Small-scale

0.552

High

254187

FZD7
Frizzled-7

1

2

High-throughput

0.536

High

349564

RASH
GTPase HRas

1

1

High-throughput

0.536

High

436108

ANXA6
Annexin A6

1

1

High-throughput

0.536

High

530185

NCAM1
Neural cell adhesion molecule 1

1

1

High-throughput

0.536

High

580445

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

3

High-throughput

0.536

High

637020

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.536

High

654659

CALX
Calnexin

1

2

High-throughput

0.536

High

656968

5HT1B
5-hydroxytryptamine receptor 1B

1

5

High-throughput

0.536

High

736016

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.536

High

808842

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.536

High

873149

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

6

High-throughput

0.536

High

885293

EPIPL
Epiplakin

1

3

High-throughput

0.536

High

943146

KC1G2
Casein kinase I isoform gamma-2

1

1

High-throughput

0.536

High

986102

KDSR
3-ketodihydrosphingosine reductase

1

3

High-throughput

0.536

High

999647

AHNK
Neuroblast differentiation-associated protein AHNAK

1

1

High-throughput

0.536

High

1045483

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.536

High

1049619

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.536

High

1060868

IMB1
Importin subunit beta-1

1

3

High-throughput

0.536

High

1202345

RETR3
Reticulophagy regulator 3

1

1

High-throughput

0.536

High

1291792

CML1
Chemerin-like receptor 1

1

17

High-throughput

0.536

High

1291804

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.536

High

275084

RENR
Renin receptor

1

0

High-throughput

0.513

High

506204

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.513

High

566449

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.513

High

873118

GAS1
Growth arrest-specific protein 1

1

0

High-throughput

0.513

High

1018304

CNTN1
Contactin-1

1

0

High-throughput

0.513

High

1021547

DLG1
Disks large homolog 1

1

0

High-throughput

0.513

High

1056281

I5P1
Inositol polyphosphate-5-phosphatase A

1

0

High-throughput

0.513

High

1160504

MEAK7
MTOR-associated protein MEAK7

1

0

High-throughput

0.513

High

1185477

EEPD1
Endonuclease/exonuclease/phosphatase family domain-containing protein 1

1

0

High-throughput

0.513

High

1245261

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.513

High

1291793

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.513

High

1291797

CEP41
Centrosomal protein of 41 kDa

1

0

High-throughput

0.513

High

476194

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

537300

DRD2
D(2) dopamine receptor

1

9

High-throughput

0.494

High

1040768

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.494

High

1291790

NECD
Necdin

1

0

High-throughput

0.493

High

134397

ACKR2
Atypical chemokine receptor 2

1

7

High-throughput

0.489

High

204721

E41L2
Band 4.1-like protein 2

1

2

High-throughput

0.489

High

274849

PALM
Paralemmin-1

1

1

High-throughput

0.489

High

326177

TSN15
Tetraspanin-15

1

4

High-throughput

0.489

High

328371

S1PR4
Sphingosine 1-phosphate receptor 4

1

14

High-throughput

0.489

High

412303

FYN
Tyrosine-protein kinase Fyn

1

3

High-throughput

0.489

High

433445

YES
Tyrosine-protein kinase Yes

1

3

High-throughput

0.489

High

433942

LYN
Tyrosine-protein kinase Lyn

1

3

High-throughput

0.489

High

443722

VIME
Vimentin

1

3

High-throughput

0.489

High

446053

CD63
CD63 antigen

1

3

High-throughput

0.489

High

451028

GNAO

1

2

High-throughput

0.489

High

523108

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

High-throughput

0.489

High

579585

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

1

High-throughput

0.489

High

600824

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

17

High-throughput

0.489

High

617136

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

4

High-throughput

0.489

High

686356

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

8

High-throughput

0.489

High

781097

OPRX
Nociceptin receptor

1

5

High-throughput

0.489

High

814586

P2RY1
P2Y purinoceptor 1

1

13

High-throughput

0.489

High

837640

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

3

High-throughput

0.489

High

871461

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

2

High-throughput

0.489

High

880507

ATP5I
ATP synthase subunit e, mitochondrial

1

1

High-throughput

0.489

High

986010

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

4

High-throughput

0.489

High

990911

ZO1
Tight junction protein ZO-1

1

1

High-throughput

0.489

High

1025194

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

High-throughput

0.489

High

1031047

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

13

High-throughput

0.489

High

1035196

ROCK1
Rho-associated protein kinase 1

1

2

High-throughput

0.489

High

1056613

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

2

High-throughput

0.489

High

1068635

PLEC
Plectin

1

2

High-throughput

0.489

High

1079211

STXB2
Syntaxin-binding protein 2

1

2

High-throughput

0.489

High

1081748

AINX
Alpha-internexin

1

3

High-throughput

0.489

High

1187558

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

1

High-throughput

0.489

High

1217493

AHNK2
Protein AHNAK2

1

1

High-throughput

0.489

High

1237214

CCYL1
Cyclin-Y-like protein 1

1

1

High-throughput

0.489

High

1237871

ENAH
Protein enabled homolog

1

1

High-throughput

0.489

High

1242189

CCNY
Cyclin-Y

1

1

High-throughput

0.489

High

1255755

MICA1
[F-actin]-monooxygenase MICAL1

1

1

High-throughput

0.489

High

1290576

MB12A
Multivesicular body subunit 12A

1

1

High-throughput

0.489

High

1291788

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.489

High

1291798

ULBP3
UL16-binding protein 3

1

1

High-throughput

0.489

High

1291808

MB12B
Multivesicular body subunit 12B

1

1

High-throughput

0.489

High

1291810

IPPK
Inositol-pentakisphosphate 2-kinase

1

3

High-throughput

0.489

High

1291812

GPR35
G-protein coupled receptor 35

1

16

High-throughput

0.489

High

1291813

GP173
Probable G-protein coupled receptor 173

1

9

High-throughput

0.489

High

1291828

TNF18
Tumor necrosis factor ligand superfamily member 18

1

1

High-throughput

0.489

High

1291829

PLAK2
PALM2-AKAP2 fusion protein

1

1

High-throughput

0.489

High

1291830

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.489

High

1291832

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.489

High

1291833

TLN1
Talin-1

1

2

High-throughput

0.489

High

1291834

CD2AP
CD2-associated protein

1

1

High-throughput

0.489

High

1291836

KC1G3
Casein kinase I isoform gamma-3

1

1

High-throughput

0.489

High

1291818

S39A1
Zinc transporter ZIP1

1

2

High-throughput

0.481

High

50787

ELOV7
Very long chain fatty acid elongase 7

1

8

Small-scale

0.479

High

163931

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

338834

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

390450

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

391096

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

545556

RAC2
Ras-related C3 botulinum toxin substrate 2

1

2

High-throughput

0.479

High

577054

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

4

High-throughput

0.479

High

795234

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

847603

BAP31
B-cell receptor-associated protein 31

1

5

High-throughput

0.479

High

890340

SC61B
Protein transport protein Sec61 subunit beta

1

4

High-throughput

0.479

High

894305

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

900792

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

917735

H4
Histone H4

1

1

High-throughput

0.479

High

926618

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

3

High-throughput

0.479

High

1087582

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

1120976

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

Small-scale

0.479

High

1198650

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1240249

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1269349

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1282611

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1291789

SEC62
Translocation protein SEC62

1

3

High-throughput

0.479

High

1291795

ELOV1
Very long chain fatty acid elongase 1

1

8

Small-scale

0.479

High

1291800

ELOV4
Very long chain fatty acid elongase 4

1

8

Small-scale

0.479

High

1291801

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.479

High

1291806

ELOV6
Very long chain fatty acid elongase 6

1

8

Small-scale

0.479

High

1291809

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1291811

ELOV3
Very long chain fatty acid elongase 3

1

8

Small-scale

0.479

High

1291817

ELOV2
Very long chain fatty acid elongase 2

1

8

Small-scale

0.479

High

1291820

TECR
Very-long-chain enoyl-CoA reductase

1

1

Small-scale

0.479

High

240906

S19A2
Thiamine transporter 1

1

0

High-throughput

0.460

High

874672

BI1
Bax inhibitor 1

1

0

High-throughput

0.460

High

329888

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

527705

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.458

High

648849

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

750411

COIL
Coilin

1

0

High-throughput

0.458

High

845663

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.458

High

941296

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1237952

VA0D2
V-type proton ATPase subunit d 2

1

0

High-throughput

0.458

High

1291794

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.458

High

1291799

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1291803

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1291821

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

360271

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.437

High

434260

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

2

High-throughput

0.437

High

617064

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

3

High-throughput

0.437

High

1067580

P2RY6
P2Y purinoceptor 6

1

14

High-throughput

0.437

High

1156669

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1171215

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1199667

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.437

High

1222071

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

1291785

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

1291805

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1291815

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

1291822

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

63541

T238L
Transmembrane protein 238-like

1

0

Small-scale

0.426

High

63229

RP1BL
Ras-related protein Rap-1b-like protein

1

1

High-throughput

0.407

High

60628

VP37C
Vacuolar protein sorting-associated protein 37C

1

0

High-throughput

0.279

Low

118065

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.279

Low

119777

ARVC
Splicing regulator ARVCF

1

0

High-throughput

0.279

Low

237616

DIAP1
Protein diaphanous homolog 1

1

0

High-throughput

0.279

Low

264734

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.279

Low

570271

NEUM
Neuromodulin

1

0

High-throughput

0.279

Low

671100

ATPD
ATP synthase subunit delta, mitochondrial

1

0

High-throughput

0.279

Low

856621

EFNA5
Ephrin-A5

1

0

High-throughput

0.279

Low

869972

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.279

Low

969516

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

0

High-throughput

0.279

Low

1036324

BIRC2
Baculoviral IAP repeat-containing protein 2

1

0

High-throughput

0.279

Low

1058604

RFTN1
Raftlin

1

0

High-throughput

0.279

Low

1082530

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

0

High-throughput

0.279

Low

1152033

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.279

Low

1160332

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1216900

RELL1
RELT-like protein 1

1

0

High-throughput

0.279

Low

1222301

RAVR1
Ribonucleoprotein PTB-binding 1

1

0

High-throughput

0.279

Low

1250947

OCC1
Overexpressed in colon carcinoma 1 protein

1

0

High-throughput

0.279

Low

1266074

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.279

Low

1283508

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.279

Low

1291367

CPNE2
Copine-2

1

0

High-throughput

0.279

Low

1291786

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.279

Low

1291787

PRRC1
Protein PRRC1

1

0

High-throughput

0.279

Low

1291791

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.279

Low

1291802

CA021
Uncharacterized protein C1orf21

1

0

High-throughput

0.279

Low

1291816

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.279

Low

1291824

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.279

Low

1291825

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.279

Low

1291826

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

0

High-throughput

0.279

Low

1291827

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

0

High-throughput

0.279

Low

1291831

CHMP3
Charged multivesicular body protein 3

1

0

High-throughput

0.279

Low

131043

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.249

Low

155424

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

231671

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.249

Low

277389

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

0

High-throughput

0.249

Low

632354

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

931790

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.249

Low

1049722

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.249

Low

1148728

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1188707

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1230324

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1291814

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1291823

UBQL2
Ubiquilin-2

1

0

High-throughput

0.249

Low

314922

GNAS3
Neuroendocrine secretory protein 55

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024