HitPredict

Interactor 1: MAEA (Q7L5Y9)
E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP)
Gene: MAEA

Interactor 2: RMD5B (Q96G75)
E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B)
Gene: RMND5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27173435, 35235311
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CTLH~CTLH
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0034657 - GID complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046872 - metal ion binding
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 396
Hs

1 393
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Last updated: 15 Jul 2024